1, 1, 1, 3, 3, 3-Hexafluoroisopropanol (HFIP) is a polar, strongly hydrogen bond-donating
solvent that has found numerous uses in organic synthesis due to its ability to stabilize ionic …

Transition-metal-catalyzed, coordination-assisted C (sp3)–H functionalization has
revolutionized synthetic planning over the past few decades as the use of these directing …

During the past decades, synthetic organic chemistry discovered that directing group
assisted C–H activation is a key tool for the expedient and siteselective construction of C–C …

Transition-metal catalyzed reactions that are able to construct complex aliphatic amines from
simple, readily available feedstocks have become a cornerstone of modern synthetic …

In 2001, our curiosity to understand the stereochemistry of C− H metalation with Pd
prompted our first studies in Pd (II)‐catalyzed asymmetric C− H activation (RSC Research …

The design of synthetic routes by retrosynthetic logic is decisively influenced by the
transformations available. Transition‐metal‐catalyzed C− H activation has emerged as a …

This Review summarizes the advancements in Pd-catalyzed C (sp3)–H activation via
various redox manifolds, including Pd (0)/Pd (II), Pd (II)/Pd (IV), and Pd (II)/Pd (0). While few …

The functionalization of C (sp3)− H bonds streamlines chemical synthesis by allowing the
use of simple molecules and providing novel synthetic disconnections. Intensive recent …

The development of methods for the functionalization of otherwise inert C–H bonds is one of
the major foci in molecular syntheses. Recent advances have significantly improved the …

As two coexisting and fast-growing research fields in modern synthetic chemistry, the
merging of organocatalysis and C–H bond functionalization is well foreseeable, and the joint …