What is known about breast cancer in young women?

JW Zhu, P Charkhchi, S Adekunte, MR Akbari - Cancers, 2023 - mdpi.com
Simple Summary Breast cancer is the most common cancer affecting women under 40 years
of age worldwide, with an increasing number of cases diagnosed each year. Despite this …

Chemotherapy-induced peripheral neurotoxicity

G Cavaletti, P Marmiroli - Current opinion in neurology, 2015 - journals.lww.com
Precise definition of CIPN clinical features can be obtained by only using validated outcome
measures. Therefore, a major aim of clinical research is to standardize CIPN assessment …

Risk of heart failure with preserved ejection fraction in older women after contemporary radiotherapy for breast cancer

H Saiki, IA Petersen, CG Scott, KR Bailey, SM Dunlay… - Circulation, 2017 - Am Heart Assoc
Background: Cardiomyocytes are resistant to radiation. However, cardiac radiation exposure
causes coronary microvascular endothelial inflammation, a perturbation implicated in the …

Safety of targeted axillary dissection after neoadjuvant therapy in patients with node-positive breast cancer

S Kuemmel, J Heil, S Bruzas, E Breit… - JAMA …, 2023 - jamanetwork.com
Importance The increasing use of neoadjuvant systemic therapy (NST) has led to substantial
pathological complete response rates in patients with initially node-positive, early breast …

Multi-omics integration analysis robustly predicts high-grade patient survival and identifies CPT1B effect on fatty acid metabolism in bladder cancer

V Vantaku, J Dong, CR Ambati, D Perera… - Clinical Cancer …, 2019 - AACR
Purpose: The perturbation of metabolic pathways in high-grade bladder cancer has not
been investigated. We aimed to identify a metabolic signature in high-grade bladder cancer …

Prediction of Distant Recurrence Using EndoPredict Among Women with ER+, HER2 Node-Positive and Node-Negative Breast Cancer Treated with Endocrine …

M Filipits, P Dubsky, M Rudas, R Greil, M Balic… - Clinical Cancer …, 2019 - AACR
Purpose: Prognostic molecular assays may aid in treatment decisions for women with
estrogen receptor (ER)-positive, HER2-negative breast cancer. The prognostic value of a 12 …

Regulation of head and neck squamous cancer stem cells by PI3K and SOX2

SB Keysar, PN Le, B Miller, BC Jackson… - Journal of the …, 2017 - academic.oup.com
Background: Not all breast cancer patients benefit from neoadjuvant or adjuvant therapy,
resulting in considerable undertreatment or overtreatment. New insights into the role of …

lncRNA TCL6 correlates with immune cell infiltration and indicates worse survival in breast cancer

Y Zhang, Z Li, M Chen, H Chen, Q Zhong, L Liang, B Li - Breast Cancer, 2020 - Springer
Background Long non-coding RNA (lncRNA) T-cell leukemia/lymphoma 6 (TCL6) has been
reported as a potential tumor suppressor. However, its expression and function in breast …

Implications of missing data on reported breast cancer mortality

JK Plichta, CN Rushing, HC Lewis, MM Rooney… - Breast cancer research …, 2023 - Springer
Background National cancer registries are valuable tools to analyze patterns of care and
clinical outcomes; yet, missing data may impact the accuracy and generalizability of these …

A prospective trial of treatment de-escalation following neoadjuvant paclitaxel/trastuzumab/pertuzumab in HER2-positive breast cancer

AG Waks, NV Desai, T Li, PD Poorvu, AH Partridge… - NPJ Breast …, 2022 - nature.com
De-escalating adjuvant therapy following pathologic complete response (pCR) to an
abbreviated neoadjuvant regimen in human epidermal growth factor receptor 2-positive …