NetREm Network Regression Embeddings reveal cell-type transcription factor coordination for gene regulation
Transcription factor (TF) coordination plays a key role in target gene (TG) regulation via
protein-protein interactions (PPIs) and DNA co-binding to regulatory elements. Single-cell …
protein-protein interactions (PPIs) and DNA co-binding to regulatory elements. Single-cell …
[HTML][HTML] A large-scale cancer-specific protein-DNA interaction network
Cancer development and progression are generally associated with dysregulation of gene
expression, often resulting from changes in transcription factor (TF) sequence or expression …
expression, often resulting from changes in transcription factor (TF) sequence or expression …
Identification and catalogue of viral transcriptional regulators in human diseases
Viral genomes encode viral transcriptional regulators (vTRs) that manipulate host gene
expression to facilitate replication and evade immune detection. Nevertheless, their role in …
expression to facilitate replication and evade immune detection. Nevertheless, their role in …
The MYB-related transcription factor MYPOP acts as a selective regulator of cancer cell growth
L Florin, J Strunk, A Hüppner, M Sial, M Plath… - 2024 - researchsquare.com
The MYB-related transcription factor and partner of profilin (MYPOP or p42POP) is a
ubiquitously expressed and understudied protein, recently discovered in restricting …
ubiquitously expressed and understudied protein, recently discovered in restricting …
Unraveling the complexity: Advanced methods in analyzing DNA, RNA, and protein interactions
ML Peixoto, E Madan - Advances in cancer research, 2024 - pubmed.ncbi.nlm.nih.gov
Exploring the intricate interplay within and between nucleic acids, as well as their
interactions with proteins, holds pivotal significance in unraveling the molecular complexities …
interactions with proteins, holds pivotal significance in unraveling the molecular complexities …
Biological-Network Guided Machine Learning for Understanding Gene Regulation in Human Brains and Disease Phenotypes From Multi-Omics Data
S Khullar - 2024 - search.proquest.com
Understanding the genetic basis of nervous system diseases, such as Alzheimer's disease
(AD), is crucial due to their profound impact on global health and individual quality of life …
(AD), is crucial due to their profound impact on global health and individual quality of life …
Viral cis-regulatory elements as sensors of cellular states and environmental cues
To withstand a hostile cellular environment and replicate, viruses must sense, interpret, and
respond to many internal and external cues. Retroviruses and DNA viruses can intercept …
respond to many internal and external cues. Retroviruses and DNA viruses can intercept …
[CITAS][C] Cutting Edge Artificial Intelligence, Spatial Transcriptomics and Proteomics Approaches to Analyze Cancer
KD Tew, PB Fisher, E Madan, R Gogna - 2024 - Elsevier