The number of scientific publications in the literature is steadily growing, containing our
knowledge in the biomedical, health, and clinical sciences. Since there is currently no …

Pathway analysis is a set of widely used tools for research in life sciences intended to give
meaning to high-throughput biological data. The methodology of these tools settles in the …

In this paper we survey methods for performing a comparative graph analysis and explain
the history, foundations and differences of such techniques of the last 50 years. While …

Parkinson's disease (PD) is a major neurodegenerative chronic disease, most likely caused
by a complex interplay of genetic and environmental factors. Information on various aspects …

Abstract Systems Bioinformatics is a relatively new approach, which lies in the intersection of
systems biology and classical bioinformatics. It focuses on integrating information across …

It is often of interest to understand how the structure of a genetic network differs between two
conditions. In this paper, each condition-specific network is modelled using the precision …

Background Fusarium head blight (FHB) caused by Fusarium graminearum Schwabe is one
of the most prevalent diseases of wheat (Triticum aestivum L.) and other small grain cereals …

Graph theory [12, 83, 86] is a relatively new branch of mathematics and the main body of
fundamental results dates back to the seminal contribution due to König [111]. Earlier …

In this study, we infer the breast cancer gene regulatory network from gene expression data.
This network is obtained from the application of the BC3Net inference algorithm to a large …

Background Ischemic cardiomyopathy (ICM) is one of the most usual causes of death
worldwide. This study aimed to find the candidate gene for ICM. Methods We studied …