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Engineering 3D hydrogels for personalized in vitro human tissue models
There is a growing interest in engineering hydrogels for 3D tissue and disease models. The
major motivation is to better mimic the physiological microenvironment of the disease and …
major motivation is to better mimic the physiological microenvironment of the disease and …
Emerging technologies for pulmonary vein isolation
FD Ramirez, VY Reddy, R Viswanathan… - Circulation …, 2020 - ahajournals.org
Atrial fibrillation is the most common sustained cardiac arrhythmia and is associated with
considerable morbidity and mortality. Electrically isolating the pulmonary veins from the left …
considerable morbidity and mortality. Electrically isolating the pulmonary veins from the left …
Selective modulation of intracellular effects of cells using pulsed electric fields
First worldwide family litigation filed litigation Critical https://patents. darts-ip. com/? family=
54480565&utm_source= google_patent&utm_medium= platform_link&utm_campaign …
54480565&utm_source= google_patent&utm_medium= platform_link&utm_campaign …
Dynamics of cell death after conventional IRE and H-FIRE treatments
High-frequency irreversible electroporation (H-FIRE) has emerged as an alternative to
conventional irreversible electroporation (IRE) to overcome the issues associated with …
conventional irreversible electroporation (IRE) to overcome the issues associated with …
In vitro cell selectivity of reversible and irreversible: electroporation in cardiac tissue
DW Hunter, G Kostecki, JM Fish… - Circulation: Arrhythmia …, 2021 - ahajournals.org
Background: Pulmonary vein isolation is a common catheter ablation technique used to treat
atrial fibrillation originating from the pulmonary veins. However, incomplete lesion formation …
atrial fibrillation originating from the pulmonary veins. However, incomplete lesion formation …
System and method for ablating a tissue site by electroporation with real-time monitoring of treatment progress
IIR Neal, RV Davalos - US Patent 10,238,447, 2019 - Google Patents
(Continued) Primary Examiner—Michael F Peffley (74) Attorney, Agent, or Firm—New River
Valley IP Law, PC; Michele L. Mayberry (57) ABSTRACT A medical system for ablating a …
Valley IP Law, PC; Michele L. Mayberry (57) ABSTRACT A medical system for ablating a …
Bursts of bipolar microsecond pulses inhibit tumor growth
Irreversible electroporation (IRE) is an emerging focal therapy which is demonstrating utility
in the treatment of unresectable tumors where thermal ablation techniques are …
in the treatment of unresectable tumors where thermal ablation techniques are …
Device and method for electroporation based treatment of stenosis of a tubular body part
The present invention relates to medical devices and meth ods for treating a lesion such as
a vascular stenosis using non-thermal irreversible electroporation (NTIRE). Embodi ments of …
a vascular stenosis using non-thermal irreversible electroporation (NTIRE). Embodi ments of …
In-vitro bipolar nano-and microsecond electro-pulse bursts for irreversible electroporation therapies
Under the influence of external electric fields, cells experience a rapid potential buildup
across the cell membrane. Above a critical threshold of electric field strength, permanent cell …
across the cell membrane. Above a critical threshold of electric field strength, permanent cell …
Targeted cellular ablation based on the morphology of malignant cells
Abstract Treatment of glioblastoma multiforme (GBM) is especially challenging due to a
shortage of methods to preferentially target diffuse infiltrative cells and therapy-resistant …
shortage of methods to preferentially target diffuse infiltrative cells and therapy-resistant …