Lipid nanodiscs for high-resolution NMR studies of membrane proteins

U Günsel, F Hagn - Chemical Reviews, 2021 - ACS Publications
Membrane proteins (MPs) play essential roles in numerous cellular processes. Because
around 70% of the currently marketed drugs target MPs, a detailed understanding of their …

Biomimetic lipid membranes: An overview on their properties and applications

N Nisticò, M Greco, MC Bruno, E Giuliano… - Applied Materials …, 2023 - Elsevier
Cell membranes are complex biological bilayer-like structures made up of various
phospholipids and proteins as main components. Biomimetic lipid membranes are model …

Solution structure of bilayer membrane-embedded proton-translocating pyrophosphatase revealed via small-angle X-ray scattering

O Shih, YQ Yeh, KF Liao, KM Li, JY Tsai, CC Li… - Materials Chemistry and …, 2023 - Elsevier
The conformations and compositions of a proton-translocating pyrophosphatase Vigna
radiata H+-PPase (VrPPase), stabilized by either detergent molecules or embedded in a …

Biophysical characterisation of SMALPs

SA Nestorow, TR Dafforn… - Biochemical Society …, 2021 - portlandpress.com
Membrane proteins such as receptors, ion channels and transport proteins are important
drug targets. The structure-based study of membrane proteins is challenging, especially …

Anabaena Sensory Rhodopsin Reconstituted in Nanodiscs as a Promising Platform for Structural Studies

S Camargo - 2023 - atrium.lib.uoguelph.ca
Membrane protein studies need an excellent membrane-mimicking reconstitution system.
Nanodiscs offer many advantages in this regard but require optimal conditions for achieving …