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Tackling the antimicrobial resistance “pandemic” with machine learning tools: a summary of available evidence
Antimicrobial resistance is recognised as one of the top threats healthcare is bound to face
in the future. There have been various attempts to preserve the efficacy of existing …
in the future. There have been various attempts to preserve the efficacy of existing …
Deciphering the relative importance of genetic elements in hypervirulent Klebsiella pneumoniae to guide countermeasure development
TA Russo, U Carlino-MacDonald, ZJ Drayer… - …, 2024 - thelancet.com
Background Quantitating the contribution of phenotype-responsible elements in
hypervirulent Klebsiella pneumoniae is needed. Methods Isogenic mutants of four …
hypervirulent Klebsiella pneumoniae is needed. Methods Isogenic mutants of four …
Clonal background and routes of plasmid transmission underlie antimicrobial resistance features of bloodstream Klebsiella pneumoniae
OO Ikhimiukor, NI Zac Soligno, IJ Akintayo… - Nature …, 2024 - nature.com
Bloodstream infections caused by the opportunistic pathogen Klebsiella pneumoniae are
associated with adverse health complications and high mortality rates. Antimicrobial …
associated with adverse health complications and high mortality rates. Antimicrobial …
What defines hypervirulent Klebsiella pneumoniae?
TD Stanton, KL Wyres - EBioMedicine, 2024 - thelancet.com
Klebsiella pneumoniae is a global pathogen with remarkable genetic, phenotypic and
pathogenic diversity. 1 Strains belonging to distinct groups of lineages cause …
pathogenic diversity. 1 Strains belonging to distinct groups of lineages cause …
Detection of cefiderocol and aztreonam/avibactam resistance in epidemic Escherichia coli ST-361 carrying blaNDM-5 and blaKPC-3 from foreign fighters …
MJ Martin, TL Luo, V Kovalchuk… - Antimicrobial Agents …, 2024 - journals.asm.org
Genomic surveillance detected clonal Escherichia coli sequence type-361 isolates carrying
bla NDM-5, bla KPC-3, bla CTX-M-15, and rmtB1 from a patient in Ukraine and four …
bla NDM-5, bla KPC-3, bla CTX-M-15, and rmtB1 from a patient in Ukraine and four …
Revisiting therapeutic options against Resistant Klebsiella Pneumoniae infection: phage therapy is key
J **ng, R Han, J Zhao, Y Zhang, M Zhang… - Microbiological …, 2025 - Elsevier
Multi-drug resistant and carbapenem-resistant hypervirulent Klebsiella pneumoniae strains
are spreading globally at an alarming rate, emerging as one of the most serious threats to …
are spreading globally at an alarming rate, emerging as one of the most serious threats to …
High frequency of acquired virulence factors in carbapenemase-producing Klebsiella pneumoniae isolates from a large German university hospital, 2013–2021
Carbapenemase-producing Klebsiella pneumoniae (CP-Kp) isolates are a public health
concern as they can cause severe hospital-acquired infections that are difficult to treat. It has …
concern as they can cause severe hospital-acquired infections that are difficult to treat. It has …
[HTML][HTML] Deep Intraclonal Analysis for the Development of Vaccines against Drug-Resistant Klebsiella pneumoniae Lineages
A Tajuelo, E Gato, J Oteo-Iglesias… - International Journal of …, 2024 - mdpi.com
Despite its medical relevance, there is no commercial vaccine that protects the population at
risk from multidrug-resistant (MDR) Klebsiella pneumoniae infections. The availability of …
risk from multidrug-resistant (MDR) Klebsiella pneumoniae infections. The availability of …
Diverse polysaccharide production and biofilm formation abilities of clinical Klebsiella pneumoniae
RL Beckman IV, E Cella, T Azarian… - npj Biofilms and …, 2024 - nature.com
Klebsiella pneumoniae infections have become a growing threat for human health. The lack
of understanding of the relationship between antibiotic resistance, mucoviscosity, and …
of understanding of the relationship between antibiotic resistance, mucoviscosity, and …
Bacteraemia associated with multiple septic localizations caused by Klebsiella pneumoniae sequence type ST660
M Jauvain, M Carrer, F Palma, C Chapuzet… - European Journal of …, 2024 - Springer
We report a case of Klebsiella pneumoniae bacteraemia in an 80-year-old man in France
with no history of travel to Asia, complicated by endogenous endophthalmitis, multiple …
with no history of travel to Asia, complicated by endogenous endophthalmitis, multiple …