Osteonecrosis of the femoral head (ONFH) is a refractory disease affecting young adults,
resulting in severe hip pain, femoral head collapse, and disabling dysfunction. By far, the …

Nuclear factor-κB (NF-κB) cell signaling pathway is essential for the progression and
development of numerous human disorders, including cancer. NF-κB signaling pathway …

Objective. Our previous results showed that icariin (ICA) could inhibit apoptosis and provide
neuroprotection against hypoxic‐ischemic brain damage (HIBD) in neonatal mice, but the …

Brain cancer is regarded as one of the most life-threatening forms of cancer worldwide.
Oxidative stress acts to derange normal brain homeostasis, thus is involved in …

Abstract Amyotrophic Lateral Sclerosis (ALS) is a fatal neurodegenerative disease that
causes significant neurodegeneration. Methylmercury (MeHg+) is a neurotoxin that induces …

Ovarian cancer (OC) is the most prevalent and deadly cancer of the female reproductive
system. Women will continue to be impacted by OC-related morbidity and mortality. Despite …

Improving the reproductive ability and fertility of male ruminants is a central concern in
animal husbandry. Phytogenic feed additives, known for their anti-inflammatory, antioxidant …

BACKGROUND Icariin (ICA), a natural flavonoid compound monomer, has multiple
pharmacological activities. However, its effect on bone defect in the context of type 1 …

Objective This study aims to investigate potential beneficial actions of icariin (ICA) on
testicular spermatogenic function in male rats with streptozotocin (STZ)-induced diabetes …

Calcium supplementation has been shown to be efficacious in mitigating the progression of
senile osteoporosis (SOP) and reducing the incidence of osteoporotic fractures resulting …