S-nitrosylation: an emerging paradigm of redox signaling

V Fernando, X Zheng, Y Walia, V Sharma, J Letson… - Antioxidants, 2019 - mdpi.com
Nitric oxide (NO) is a highly reactive molecule, generated through metabolism of L-arginine
by NO synthase (NOS). Abnormal NO levels in mammalian cells are associated with multiple …

The role of oxidative stress in the pathophysiology of gestational diabetes mellitus

M Lappas, U Hiden, G Desoye, J Froehlich… - Antioxidants & redox …, 2011 - liebertpub.com
Normal human pregnancy is considered a state of enhanced oxidative stress. In pregnancy,
it plays important roles in embryo development, implantation, placental development and …

[HTML][HTML] Aberrant protein s-nitrosylation in neurodegenerative diseases

T Nakamura, S Tu, MW Akhtar, CR Sunico, S Okamoto… - Neuron, 2013 - cell.com
S-Nitrosylation is a redox-mediated posttranslational modification that regulates protein
function via covalent reaction of nitric oxide (NO)-related species with a cysteine thiol group …

Human placental trophoblast invasion and differentiation: a particular focus on Wnt signaling

M Knöfler, J Pollheimer - Frontiers in genetics, 2013 - frontiersin.org
Wingless ligands, a family of secreted proteins, are critically involved in organ development
and tissue homeostasis by ensuring balanced rates of stem cell proliferation, cell death and …

Extravillous trophoblast and decidual natural killer cells: a remodelling partnership

AE Wallace, R Fraser… - Human reproduction …, 2012 - academic.oup.com
BACKGROUND During pregnancy, maternal uterine spiral arteries (SAs) are remodelled
from minimal-flow, high-resistance vessels into larger diameter vessels with low resistance …

Post-translational modification and regulation of actin

JR Terman, A Kashina - Current opinion in cell biology, 2013 - Elsevier
Many of the best-studied actin regulatory proteins use non-covalent means to modulate the
properties of actin. Yet, actin is also susceptible to covalent modifications of its amino acids …

[HTML][HTML] Role of nitric oxide in placental vascular development and function

BJ Krause, MA Hanson, P Casanello - Placenta, 2011 - Elsevier
Nitric oxide (NO) is one of the most pleiotropic signaling molecules at systemic and cellular
levels, participating in vascular tone regulation, cellular respiration, proliferation, apoptosis …

NO signals in the haze: nitric oxide signalling in plant defence

M Leitner, E Vandelle, F Gaupels, D Bellin… - Current opinion in plant …, 2009 - Elsevier
Nitric oxide (NO) is gaining increasing attention as a regulator of diverse (patho-)
physiological processes in plants. Although this molecule has been described as playing a …

[HTML][HTML] Perspective: L-arginine and L-citrulline supplementation in pregnancy: a potential strategy to improve birth outcomes in low-resource settings

AM Weckman, CR McDonald, JAB Baxter… - Advances in …, 2019 - Elsevier
The available data support the hypothesis that L-arginine or L-citrulline supplementation
would be suitable for implementation in resource-constrained settings and will enhance …

Actin filaments—A target for redox regulation

C Wilson, JR Terman, C González‐Billault… - …, 2016 - Wiley Online Library
Actin and its ability to polymerize into dynamic filaments is critical for the form and function of
cells throughout the body. While multiple proteins have been characterized as affecting actin …