[HTML][HTML] Metaorganisms in extreme environments: do microbes play a role in organismal adaptation?

C Bang, T Dagan, P Deines, N Dubilier, WJ Duschl… - Zoology, 2018 - Elsevier
From protists to humans, all animals and plants are inhabited by microbial organisms. There
is an increasing appreciation that these resident microbes influence the fitness of their plant …

Looking Down on NF-κB

LM Williams, TD Gilmore - Molecular and Cellular Biology, 2020 - Taylor & Francis
The diversified NF-κB transcription factor family has been extensively characterized in
organisms ranging from flies to humans. However, homologs of NF-κB and many upstream …

Microbiota mediated plasticity promotes thermal adaptation in the sea anemone Nematostella vectensis

L Baldassarre, H Ying, AM Reitzel… - Nature …, 2022 - nature.com
At the current rate of climate change, it is unlikely that multicellular organisms will be able to
adapt to changing environmental conditions through genetic recombination and natural …

NF‐κB: where did it come from and why?

TD Gilmore, FS Wolenski - Immunological reviews, 2012 - Wiley Online Library
The vast majority of research on nuclear factor κB (NF‐κB) signaling in the past 25 years has
focused on its roles in normal and disease‐related processes in vertebrates, especially mice …

Going where traditional markers have not gone before: utility of and promise for RAD sequencing in marine invertebrate phylogeography and population genomics

AM Reitzel, S Herrera, MJ Layden… - Molecular …, 2013 - Wiley Online Library
Abstract Characterization of large numbers of single‐nucleotide polymorphisms (SNP s)
throughout a genome has the power to refine the understanding of population demographic …

[PDF][PDF] Signaling in the innate immune response

DH Kim - 2015 - dspace.mit.edu
The maintenance of cellular and organismal homeostasis in the face of changes in the
environment is essential for survival. Pathogenic microorganisms represent one type of …

NFκB: a promising target for natural products in cancer chemoprevention

S Luqman, JM Pezzuto - Phytotherapy Research, 2010 - Wiley Online Library
The transcription factor nuclear factor kappa B (NFκB) is found in nearly all animal cell types.
It is involved in cellular responses to stimuli such as stress, cytokines, free radicals …

Transcription factor NF-κB is modulated by symbiotic status in a sea anemone model of cnidarian bleaching

KM Mansfield, NM Carter, L Nguyen, PA Cleves… - Scientific reports, 2017 - nature.com
Transcription factor NF-κB plays a central role in immunity from fruit flies to humans, and NF-
κB activity is altered in many human diseases. To investigate a role for NF-κB in immunity …

Massively Parallel RNA Sequencing Identifies a Complex Immune Gene Repertoire in the lophotrochozoan Mytilus edulis

EER Philipp, L Kraemer, F Melzner, AJ Poustka… - PloS one, 2012 - journals.plos.org
The marine mussel Mytilus edulis and its closely related sister species are distributed world-
wide and play an important role in coastal ecology and economy. The diversification in …

Sea anemone model has a single Toll-like receptor that can function in pathogen detection, NF-κB signal transduction, and development

JJ Brennan, JL Messerschmidt, LM Williams… - Proceedings of the …, 2017 - pnas.org
In organisms from insects to vertebrates, Toll-like receptors (TLRs) are primary pathogen
detectors that activate downstream pathways, specifically those that direct expression of …