[HTML][HTML] The anatomy of pain and suffering in the brain and its clinical implications

D De Ridder, D Adhia, S Vanneste - Neuroscience & Biobehavioral …, 2021 - Elsevier
Pain is an unpleasant sensory and emotional experience associated with actual or potential
tissue damage. Chronic pain, with a prevalence of 20–30% is the major cause of human …

Deep brain stimulation: current challenges and future directions

AM Lozano, N Lipsman, H Bergman, P Brown… - Nature Reviews …, 2019 - nature.com
The clinical use of deep brain stimulation (DBS) is among the most important advances in
the clinical neurosciences in the past two decades. As a surgical tool, DBS can directly …

First-in-human prediction of chronic pain state using intracranial neural biomarkers

P Shirvalkar, J Prosky, G Chin, P Ahmadipour… - Nature …, 2023 - nature.com
Chronic pain syndromes are often refractory to treatment and cause substantial suffering
and disability. Pain severity is often measured through subjective report, while objective …

Pain and the triple network model

D De Ridder, S Vanneste, M Smith, D Adhia - Frontiers in neurology, 2022 - frontiersin.org
Acute pain is a physiological response that causes an unpleasant sensory and emotional
experience in the presence of actual or potential tissue injury. Anatomically and …

When pain gets stuck: the evolution of pain chronification and treatment resistance

D Borsook, AM Youssef, L Simons, I Elman… - Pain, 2018 - journals.lww.com
It is well-recognized that, despite similar pain characteristics, some people with chronic pain
recover, whereas others do not. In this review, we discuss possible contributions and …

Brain stimulation: a therapeutic approach for the treatment of neurological disorders

JA Camacho‐Conde… - CNS Neuroscience …, 2022 - Wiley Online Library
Brain stimulation has become one of the most acceptable therapeutic approaches in recent
years and a powerful tool in the remedy against neurological diseases. Brain stimulation is …

Role of the anterior cingulate cortex in translational pain research

X **ao, M Ding, YQ Zhang - Neuroscience bulletin, 2021 - Springer
As the most common symptomatic reason to seek medical consultation, pain is a complex
experience that has been classified into different categories and stages. In pain processing …

[HTML][HTML] Stroke-induced central pain: overview of the mechanisms, management, and emerging targets of central post-stroke pain

AT Mohanan, S Nithya, Y Nomier, DA Hassan, AM Jali… - Pharmaceuticals, 2023 - mdpi.com
The incidence of stroke plays the foremost role in the genesis of central neuropathic pain.
Central post-stroke pain (CPSP) is a central pain arising from a vascular lesion in the central …

Beyond trial‐and‐error: Individualizing therapeutic transcranial neuromodulation for chronic pain

D Ciampi de Andrade… - European journal of …, 2023 - Wiley Online Library
Abstract Background and Objective Repetitive transcranial magnetic stimulation (rTMS)
applied to the motor cortex provides supplementary relief for some individuals with chronic …

Closing the loop in psychiatric deep brain stimulation: physiology, psychometrics, and plasticity

AS Widge - Neuropsychopharmacology, 2024 - nature.com
Deep brain stimulation (DBS) is an invasive approach to precise modulation of
psychiatrically relevant circuits. Although it has impressive results in open-label psychiatric …