Recent development in preparation reactivity and biological activity of enaminoketones and enaminothiones and their utilization to prepare heterocyclic compounds

G Negri, C Kascheres… - Journal of heterocyclic …, 2004 - Wiley Online Library
Enaminoketones and esters are gaining increased interest, particularly cyclic‐β‐
enaminoesters, which are known as important intermediates for the synthesis of …

Recent developments in chemical reactivity of N, N-dimethylenamino ketones as synthons for various heterocycles

HM Gaber, MC Bagley, ZA Muhammad, SM Gomha - RSC advances, 2017 - pubs.rsc.org
The current review presents recent progress in the utility of N, N-dimethyl enaminones as
building blocks for a diverse range of acyclic, carbocyclic, five-and six-membered …

Thiazole-5-carbaldehyde Synthesis by Cascade Annulation of Enaminones and KSCN with Dess–Martin Periodinane Reagent

K Chen, B Zhao, Y Liu, JP Wan - The Journal of Organic …, 2022 - ACS Publications
The Dess–Martin periodinane (DMP) reagent-mediated reactions of tertiary enaminones
with potassium thiocyanate for the synthesis of thiazole-5-carbaldehydes are developed …

Synthesis and biological evaluation of novel pyrazole derivatives with anticancer activity

A Balbi, M Anzaldi, C Macciò, C Aiello, M Mazzei… - European journal of …, 2011 - Elsevier
We synthesized thirty-six novel pyrazole derivatives and studied their antiproliferative activity
in human ovarian adenocarcinoma A2780 cells, human lung carcinoma A549 cells, and …

Domino Reactions Based on Combinatorial Bond Transformations in Electron‐Deficient Tertiary Enamines

JP Wan, Y Gao - The Chemical Record, 2016 - Wiley Online Library
Electron‐deficient enamines such as enaminones and enaminoesters are moieties showing
widespread application in organic synthesis. Among the various available electron‐deficient …

[PDF][PDF] Dimethylformamide dimethyl acetal as a building block in heterocyclic synthesis

FA Abu‐Shanab, SM Sherif… - Journal of Heterocyclic …, 2009 - researchgate.net
N, N-dimethylformamide dimethyl acetal (DMFDMA)(1) is also called 1, 1-dimethoxy-N, N-
dimethylmethylamine and 1, 1-dimethoxytrimethylamine. The molecular formula (CH3) …

Synthesis of 2, 3-Dialkyl-5-hydroxybenzofurans via a One-pot, Three-step Reaction Sequence of 2-Monosubstituted 1, 3-Diketones and 1, 4-Benzoquinones

Q Dong, YH Yang, XJ Lv, JH Liu… - The Journal of Organic …, 2024 - ACS Publications
An economical one-pot, three-step reaction sequence of readily available 2-
monosubstituted 1, 3-diketones and 1, 4-benzoquinones has been explored for the facile …

Copper(II) Bromide/Boron Trifluoride Etherate‐Cocatalyzed Cyclization of Ketene Dithioacetals and p‐Quinones: a Mild and General Approach to Polyfunctionalized …

Y Liu, M Wang, H Yuan, Q Liu - Advanced Synthesis & Catalysis, 2010 - Wiley Online Library
A new application of copper (II) bromide‐activated ketene dithioacetals as nucleophiles in
organic chemistry has been developed. Under the cocatalysis of copper (II) bromide (2.0 …

Studies with 1‐functionally substituted alkyl azoles: Novel synthesis of functionally substituted azolylbenzimidazoles and functionally substituted azolyl‐1, 2, 4 …

M Abdel‐Megid, MH Elnagdi… - Journal of heterocyclic …, 2002 - Wiley Online Library
Abstract ω‐Azolylacetophenones 1 and 2 react with dimethylformamide dimethylacetal to
yield enaminones 7, 8 that were converted into azolylazoles via reaction with hydrazine and …

[PDF][PDF] Chemistry of carbofunctionally substituted hydrazones

AZA Elassar, HH Dib, NA Al-Awadi, MH Elnagdi - Arkivoc, 2007 - arkat-usa.org
Synthetic approaches and chemical reactivity of title compounds since 1894 to date are
reported. Emphasis is placed on pinpointing old literature reports that need reinspection in …