The central amygdala (CeA) plays a central role in physiologic and behavioral responses to
fearful stimuli, stressful stimuli, and drug-related stimuli. The CeA receives dense inputs from …

The main characteristic of alcohol use disorder is the consumption of large quantities of
alcohol despite the negative consequences. The transition from the moderate use of alcohol …

Continued seeking and drinking of alcohol despite adverse legal, health, economic, and
societal consequences is a central hallmark of human alcohol use disorders. This …

Proprioceptive sensory signals inform the CNS of the consequences of motor acts, but
effective motor planning involves internal neural systems capable of anticipating actual …

Immune or brain proinflammatory signaling has been linked to some of the behavioral
effects of alcohol. Immune signaling appears to regulate voluntary ethanol intake in rodent …

This review gives a basic introduction to the biology of protein kinase C, one of the first
calcium-dependent kinases to be discovered. We review the structure and function of protein …

Ethanol's effects on intracellular signaling pathways contribute to acute effects of ethanol as
well as to neuroadaptive responses to repeated ethanol exposure. In this chapter we review …

Background: Alcoholism is characterized by compulsive alcohol intake, but this critical
feature of alcoholism is seldom captured in preclinical studies. Here, we evaluated whether …

Background Current models of compulsive‐like quinine‐adulterated alcohol (QuA) drinking
in mice, if improved, could be more useful for uncovering the neural mechanisms of …

It is increasingly recognized that studying drug taking in laboratory animals does not equate
to studying genuine addiction, characterized by loss of control over drug use. This has …