The importance of heterogeneity to the epidemiology of tuberculosis
Although less well-recognized than for other infectious diseases, heterogeneity is a defining
feature of tuberculosis (TB) epidemiology. To advance toward TB elimination, this …
feature of tuberculosis (TB) epidemiology. To advance toward TB elimination, this …
Progression from latent infection to active disease in dynamic tuberculosis transmission models: a systematic review of the validity of modelling assumptions
Mathematical modelling is commonly used to evaluate infectious disease control policy and
is influential in sha** policy and budgets. Mathematical models necessarily make …
is influential in sha** policy and budgets. Mathematical models necessarily make …
Self-clearance of Mycobacterium tuberculosis infection: implications for lifetime risk and population at-risk of tuberculosis disease
JC Emery, AS Richards, KD Dale… - … of the Royal …, 2021 - royalsocietypublishing.org
Background: it is widely assumed that individuals with Mycobacterium tuberculosis (Mtb)
infection remain at lifelong risk of tuberculosis (TB) disease. However, there is substantial …
infection remain at lifelong risk of tuberculosis (TB) disease. However, there is substantial …
Quantifying the rates of late reactivation tuberculosis: a systematic review
The risk of tuberculosis is greatest soon after infection, but Mycobacterium tuberculosis can
remain in the body latently, and individuals can develop disease in the future, sometimes …
remain in the body latently, and individuals can develop disease in the future, sometimes …
Profiling Mycobacterium tuberculosis transmission and the resulting disease burden in the five highest tuberculosis burden countries
Background Tuberculosis (TB) control efforts are hampered by an imperfect understanding
of TB epidemiology. The true age distribution of disease is unknown because a large …
of TB epidemiology. The true age distribution of disease is unknown because a large …
Using molecular testing and whole-genome sequencing for tuberculosis diagnosis in a low-burden setting: a cost-effectiveness analysis using transmission-dynamic …
T Mugwagwa, I Abubakar, PJ White - Thorax, 2021 - thorax.bmj.com
Background Despite progress in TB control in low-burden countries like England and Wales,
there are still diagnostic delays. Molecular testing and/or whole-genome sequencing (WGS) …
there are still diagnostic delays. Molecular testing and/or whole-genome sequencing (WGS) …
Assortative social mixing and sex disparities in tuberculosis burden
Globally, men have higher tuberculosis (TB) burden but the mechanisms underlying this sex
disparity are not fully understood. Recent surveys of social mixing patterns have established …
disparity are not fully understood. Recent surveys of social mixing patterns have established …
Economic and modeling evidence for tuberculosis preventive therapy among people living with HIV: A systematic review and meta-analysis
Background Human immunodeficiency virus (HIV) is the strongest known risk factor for
tuberculosis (TB) through its impairment of T-cell immunity. Tuberculosis preventive …
tuberculosis (TB) through its impairment of T-cell immunity. Tuberculosis preventive …
Inferring end-to-end latency in live videos
This paper provides an end-to-end latency model of real-time generated live videos
composed of sub-models of capturing, encoding, network, decoding, rendering, and display …
composed of sub-models of capturing, encoding, network, decoding, rendering, and display …
Achieving a “step change” in the tuberculosis epidemic through comprehensive community-wide intervention: a model-based analysis
Background Global progress towards reducing tuberculosis (TB) incidence and mortality has
consistently lagged behind the World Health Organization targets leading to a perception …
consistently lagged behind the World Health Organization targets leading to a perception …