Functional dyspepsia

AC Ford, S Mahadeva, MF Carbone, BE Lacy… - The Lancet, 2020 - thelancet.com
Dyspepsia is a complex of symptoms referable to the gastroduodenal region of the
gastrointestinal tract and includes epigastric pain or burning, postprandial fullness, or early …

Functional gastrointestinal disorders: advances in understanding and management

CJ Black, DA Drossman, NJ Talley, J Ruddy, AC Ford - The Lancet, 2020 - thelancet.com
Gastrointestinal symptoms are highly prevalent, but many people who have them will have
no organic explanation for their symptoms. Most of these people will be labelled as having a …

Gastroduodenal disorders

V Stanghellini, FKL Chan, WL Hasler, JR Malagelada… - Gastroenterology, 2016 - Elsevier
Symptoms that can be attributed to the gastroduodenal region represent one of the main
subgroups among functional gastrointestinal disorders. A slightly modified classification into …

Efficacy of Bifidobacterium animalis subsp. lactis BL-99 in the treatment of functional dyspepsia: a randomized placebo-controlled clinical trial

Q Zhang, G Li, W Zhao, X Wang, J He, L Zhou… - Nature …, 2024 - nature.com
Current treatment for functional dyspepsia (FD) has limited and unsustainable efficacy.
Probiotics have the sustainable potential to alleviate FD. This randomized controlled clinical …

Novel concepts in the pathophysiology and treatment of functional dyspepsia

L Wauters, NJ Talley, MM Walker, J Tack, T Vanuytsel - Gut, 2020 - gut.bmj.com
Emerging data increasingly point towards the duodenum as a key region underlying the
pathophysiology of functional dyspepsia (FD), one of the most prevalent functional GI …

Functional dyspepsia

P Enck, F Azpiroz, G Boeckxstaens… - Nature Reviews …, 2017 - nature.com
Functional dyspepsia is one of the most prevalent functional gastrointestinal disorders.
Functional dyspepsia comprises three subtypes with presumed different pathophysiology …

Evidence-based clinical practice guidelines for functional dyspepsia 2021

H Miwa, A Nagahara, A Asakawa, M Arai… - Journal of …, 2022 - Springer
Background Functional dyspepsia (FD) is a disorder that presents with chronic dyspepsia,
which is not only very common but also highly affects quality of life of the patients. In Japan …

Epidemiology, clinical characteristics, and associations for symptom-based Rome IV functional dyspepsia in adults in the USA, Canada, and the UK: a cross-sectional …

I Aziz, OS Palsson, H Törnblom, AD Sperber… - The lancet …, 2018 - thelancet.com
Background The population prevalence, clinical characteristics, and associations for Rome
IV functional dyspepsia are not known. Following the publication of the Rome IV criteria for …

Effective and safe proton pump inhibitor therapy in acid-related diseases–a position paper addressing benefits and potential harms of acid suppression

C Scarpignato, L Gatta, A Zullo, C Blandizzi… - BMC medicine, 2016 - Springer
Background The introduction of proton pump inhibitors (PPIs) into clinical practice has
revolutionized the management of acid-related diseases. Studies in primary care and …

The mucosal immune system: master regulator of bidirectional gut–brain communications

N Powell, MM Walker, NJ Talley - Nature reviews Gastroenterology & …, 2017 - nature.com
Communication between the brain and gut is not one-way, but a bidirectional highway
whereby reciprocal signals between the two organ systems are exchanged to coordinate …