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The role of immune cells and mediators in preeclampsia
Preeclampsia is a hypertensive disorder of major concern in pregnancy than can lead to
intrauterine growth restriction, placental abruption and stillbirth. The pathophysiology of …
intrauterine growth restriction, placental abruption and stillbirth. The pathophysiology of …
T helper (Th) cell profiles in pregnancy and recurrent pregnancy losses: Th1/Th2/Th9/Th17/Th22/Tfh cells
W Wang, N Sung, A Gilman-Sachs… - Frontiers in …, 2020 - frontiersin.org
During pregnancy, various immune effectors and molecules participating in the immune-
microenvironment establish specific maternal tolerance toward the semi-allogeneic fetus …
microenvironment establish specific maternal tolerance toward the semi-allogeneic fetus …
Lachnospiraceae-derived butyrate mediates protection of high fermentable fiber against placental inflammation in gestational diabetes mellitus
S Huang, J Chen, Z Cui, K Ma, D Wu, J Luo, F Li… - Science …, 2023 - science.org
Inflammation-associated insulin resistance is a key trigger of gestational diabetes mellitus
(GDM), but the underlying mechanisms and effective interventions remain unclear. Here, we …
(GDM), but the underlying mechanisms and effective interventions remain unclear. Here, we …
[HTML][HTML] The two-stage placental model of preeclampsia: An update
AC Staff - Journal of reproductive immunology, 2019 - Elsevier
Early-onset preeclampsia has been linked to poor placentation and fetal growth restriction,
whereas late-onset preeclampsia was suggested to result from maternal factors. We have …
whereas late-onset preeclampsia was suggested to result from maternal factors. We have …
[HTML][HTML] Failure of physiological transformation and spiral artery atherosis: their roles in preeclampsia
Physiological transformation with remodeling of the uteroplacental spiral arteries is key to a
successful placentation and normal placental function. It is an intricate process that involves …
successful placentation and normal placental function. It is an intricate process that involves …
The immunobiology of preterm labor and birth: intra-amniotic inflammation or breakdown of maternal–fetal homeostasis
In brief The syndrome of preterm labor comprises multiple established and novel etiologies.
This review summarizes the distinct immune mechanisms implicated in preterm labor and …
This review summarizes the distinct immune mechanisms implicated in preterm labor and …
Cytokines, hormones and cellular regulatory mechanisms favoring successful reproduction
Its semi-allogeneic nature renders the conceptus vulnerable to attack by the maternal
immune system. Several protective mechanisms operate during gestation to correct the …
immune system. Several protective mechanisms operate during gestation to correct the …
Pathogenesis of preterm birth: bidirectional inflammation in mother and fetus
Abstract Preterm birth (PTB) complicates 5–18% of pregnancies globally and is a leading
cause of maternal and fetal morbidity and mortality. Most PTB is spontaneous and idiopathic …
cause of maternal and fetal morbidity and mortality. Most PTB is spontaneous and idiopathic …
CCL2: An important cytokine in normal and pathological pregnancies: A review
Z Lin, JL Shi, M Chen, ZM Zheng, MQ Li… - Frontiers in …, 2023 - frontiersin.org
CC motif ligand 2 (CCL2), also known as monocytic chemotactic protein 1 (MCP-1), is an
integral chemotactic factor which recruits macrophages for the immune response. Together …
integral chemotactic factor which recruits macrophages for the immune response. Together …
[HTML][HTML] Endometrial immune dysfunction in recurrent pregnancy loss
C Ticconi, A Pietropolli, N Di Simone… - International journal of …, 2019 - mdpi.com
Recurrent pregnancy loss (RPL) represents an unresolved problem for contemporary
gynecology and obstetrics. In fact, it is not only a relevant complication of pregnancy, but is …
gynecology and obstetrics. In fact, it is not only a relevant complication of pregnancy, but is …