T Regulatory cells (Tregs) can have both protective and pathological roles. They maintain
immune homeostasis and inhibit immune responses in various diseases, including cancer …

Colorectal cancer (CRC) is a heterogeneous disease with one of the highest rates of
incidence and mortality among cancers worldwide. Understanding the CRC tumor …

Background There has been a long-standing need in biomedical research for a method that
quantifies the normally mixed composition of leukocytes beyond what is possible by simple …

Background CV9103 is a prostate-cancer vaccine containing self-adjuvanted mRNA
(RNActive®) encoding the antigens PSA, PSCA, PSMA, and STEAP1. This phase I/IIa study …

The culmination of over a century's work to understand the role of the immune system in
tumor control has led to the recent advances in cancer immunotherapies that have resulted …

Regulatory T (Treg) cells, possess a strategic role in the maintenance of immune
homeostasis, and their function has been closely linked to development of diverse …

Is there any reason to write a third book on the topic of oxygen-ozone therapy? The first was
written four years ago for italian physicians, who, for some time, had complained about the …

Regulatory T cells (Tregs) constitute an attractive therapeutic target given their essential role
in controlling autoimmunity. However, recent animal studies provide evidence for functional …

Adversity, particularly in early life, can cause illness. Clues to the responsible mechanisms
may lie with the discovery of molecular signatures of stress, some of which include …

At the present time, regulatory T cells (Tregs) are an integral part of immunology but the
route from discovery of “suppressive” lymphocytes in the 1980s to the current established …