Major depressive disorder (MDD) is characterized by a multitude of psychopathological
symptoms including affective, cognitive, perceptual, sensorimotor, and social. The neuronal …

The involvement of central and peripheral inflammation in the pathogenesis and prognosis
of major depressive disorder (MDD) has been demonstrated. The increase of pro …

Major depressive disorder (MDD) affects millions of individuals worldwide, leading to
considerable social and economic costs. Despite advancements in pharmacological …

Background: Knowledge about the pathogenesis of depression and treatments for this
disease are lacking. Epigenetics-related circRNAs are likely involved in the mechanism of …

Psychological stress is often linked to depression and can also impact the immune system,
illustrating the interconnectedness of mental health and immune function. Hematopoietic …

Rationale: Recent evidence highlights the pivotal role of mitochondrial dysfunction in mood
disorders, but the mechanism involved remains unclear. We studied whether the …

Major depressive disorder (MDD) has a high prevalence and is a major contributor to the
global burden of disease. This psychiatric disorder results from a complex interaction …

Background Zuranolone is recognised as a promising antidepressant agent. Our study
aimed to investigate the efficacy and safety of zuranolone in treating major depressive …

Background and purpose Although a large collection of data has shown that ginsenosides,
the major active ingredients from Ginseng, have neuroprotective and anti-depressant effect …

Previous studies have shown that major depressive disorder (MDD) patients exhibit
structural and functional impairments, but few studies have investigated changes in higher …