In vivo near-infrared (NIR) fluorescence imaging is an emerging biomedical imaging
modality for use in both fundamental scientific research and clinical practice. Owing to …

A variety of targeted nanoparticles were developed for the diagnosis and therapy of
orthotopic and metastatic bone tumors during the past decade. This critical review will focus …

Strong oxygen dependence, poor tumor targeting, and limited treatment depth have been
considered as the “Achilles' heels” facing the clinical usage of photodynamic therapy (PDT) …

Conspectus Near-infrared (NIR) fluorescence light has been widely utilized in clinical
imaging by providing surgeons highly specific images of target tissue. The “NIR window” …

Phototheranostics stem from the recent advances in nanomedicines and bioimaging to
diagnose and treat human diseases. Since tumors' diversity, heterogeneity, and instability …

Structure-inherent targeting (SIT) agents are of particular importance for clinical precision
medicine; however, there still exists a great lack of SIT phototheranostics for simultaneous …

Nile red and Nile blue are highly fluorescent and photostable organic dyes from the benzo
[a] phenoxazine family. They have been used as histological stains for imaging lysosomes …

Abstract Development of novel nanomaterials for disease theranostics represents an
important direction in chemistry and precision medicine. Fluorescent molecular probes in the …

Drug-induced hepatotoxicity represents an important challenge for safety in drug
development. The production of peroxynitrite (ONOO–) is proposed as an early sign in the …

Cancer is a group of diseases responsible for the major causes of mortality and morbidity
among people of all ages. Even though medical sciences have made enormous growth …