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Nonspecific binding—fundamental concepts and consequences for biosensing applications
A Frutiger, A Tanno, S Hwu, RF Tiefenauer… - Chemical …, 2021 - ACS Publications
Nature achieves differentiation of specific and nonspecific binding in molecular interactions
through precise control of biomolecules in space and time. Artificial systems such as …
through precise control of biomolecules in space and time. Artificial systems such as …
Glycomimetics versus multivalent glycoconjugates for the design of high affinity lectin ligands
One could certainly highlight a conceptual resemblance between social interactions as the
basis of societies and civilizations and the ability of molecules to interact in a noncovalent …
basis of societies and civilizations and the ability of molecules to interact in a noncovalent …
Multivalency as a chemical organization and action principle
Multivalent interactions can be applied universally for a targeted strengthening of an
interaction between different interfaces or molecules. The binding partners form cooperative …
interaction between different interfaces or molecules. The binding partners form cooperative …
Nanoscale forces and their uses in self‐assembly
The focus of nanoscience and nanotechnology is gradually shifting from the synthesis of
individual components to their assembly into larger systems and nanostructured materials …
individual components to their assembly into larger systems and nanostructured materials …
Binding mechanisms in supramolecular complexes
HJ Schneider - Angewandte Chemie International Edition, 2009 - Wiley Online Library
Forces to reckon with: Supramolecular complexes, such as the one shown, are normally
based on a combination of different interactions such as ion pairing, hydrogen bonds, and …
based on a combination of different interactions such as ion pairing, hydrogen bonds, and …
Heteromultivalent peptide recognition by co-assembly of cyclodextrin and calixarene amphiphiles enables inhibition of amyloid fibrillation
Z Xu, S Jia, W Wang, Z Yuan, B Jan Ravoo, DS Guo - Nature chemistry, 2019 - nature.com
Heteromultivalency, which involves the simultaneous interactions of more than one type of
ligand with more than one type of receptor, is ubiquitous in living systems and provides a …
ligand with more than one type of receptor, is ubiquitous in living systems and provides a …
Designing super selectivity in multivalent nano-particle binding
FJ Martinez-Veracoechea, D Frenkel - Proceedings of the National …, 2011 - pnas.org
A key challenge in nano-science is to design ligand-coated nano-particles that can bind
selectively to surfaces that display the cognate receptors above a threshold (surface) …
selectively to surfaces that display the cognate receptors above a threshold (surface) …
Multivalency and cooperativity in supramolecular chemistry
Multivalent interactions, which rely upon noncovalent bonds, are essential ingredients in the
mediation of biological processes, as well as in the construction of complex (super) …
mediation of biological processes, as well as in the construction of complex (super) …
Pathogen inhibition by multivalent ligand architectures
S Bhatia, LC Camacho, R Haag - Journal of the American …, 2016 - ACS Publications
Interfacial multivalent interactions at pathogen–cell interfaces can be competitively inhibited
by multivalent scaffolds that prevent pathogen adhesion to the cells during the initial stages …
by multivalent scaffolds that prevent pathogen adhesion to the cells during the initial stages …
Equilibrium ring-closing metathesis
Ring-closing metathesis (RCM) of dienes is one of the most important methodologies now in
use for the assembly of cyclic organic compounds. First employed by Villemin and by Tsuji …
use for the assembly of cyclic organic compounds. First employed by Villemin and by Tsuji …