RNA base editing refers to the rewriting of genetic information within an intact RNA molecule
and serves various functions, such as evasion of the endogenous immune system and …

With the advancement of sequencing technologies and bioinformatics, over than 170
different RNA modifications have been identified. However, only a few of these modifications …

Conspectus Post-transcriptional modifications are ubiquitous in both protein-coding and
noncoding RNAs (ncRNAs), playing crucial functional roles in diverse biological processes …

Abstract Adenosine Deaminases Acting on RNA (ADARs) are enzymes that catalyze the
conversion of adenosine to inosine in RNA duplexes. These enzymes can be harnessed to …

Nonsense mutations are genetic mutations that create premature termination codons
(PTCs), leading to truncated, defective proteins in diseases such as cystic fibrosis …

Abstract Adenosine Deaminases Acting on RNA (ADARs) catalyze the deamination of
adenosine to inosine in double-stranded RNA (dsRNA). ADARs' ability to recognize and edit …

Adenosine Deaminases Acting on RNA (ADARs) are members of a family of RNA editing
enzymes that catalyze the conversion of adenosine into inosine in double-stranded RNA …

RNA-binding proteins (RBPs) regulate the generation of circular RNAs (circRNAs) by
participating in the reverse splicing of circRNA and thereby influencing circRNA function in …

Custom RNA base editing using the endogenous human Adenosine Deaminase Acting on
RNA (ADAR) enzyme presents a promising approach for precision therapeutics, alleviating …

Adenosine deaminases acting on RNA (ADAR) are a family of enzymes responsible for the
hydrolytic deamination of adenosine (A) to inosine (I), specifically in double-stranded RNA …