A comprehensive analysis and anti-cancer activities of quercetin in ROS-mediated cancer and cancer stem cells
Reactive oxygen species (ROS) induce carcinogenesis by causing genetic mutations,
activating oncogenes, and increasing oxidative stress, all of which affect cell proliferation …
activating oncogenes, and increasing oxidative stress, all of which affect cell proliferation …
[HTML][HTML] Advanced implications of nanotechnology in disease control and environmental perspectives
Nanotechnology encompasses a wide range of devices derived from biology, engineering,
chemistry, and physics, and this scientific field is composed of great collaboration among …
chemistry, and physics, and this scientific field is composed of great collaboration among …
Amentoflavone derivatives significantly act towards the main protease (3CLPRO/MPRO) of SARS-CoV-2: in silico admet profiling, molecular docking, molecular …
SARS-CoV-2 is the foremost culprit of the novel coronavirus disease 2019 (nCoV-19 and/or
simply COVID-19) and poses a threat to the continued life of humans on the planet and …
simply COVID-19) and poses a threat to the continued life of humans on the planet and …
Natural flavonoids effectively block the CD81 receptor of hepatocytes and inhibit HCV infection: A computational drug development approach
Hepatitis C virus (HCV) infection is a major public health concern, and almost two million
people are infected per year globally. This is occurred by the diverse spectrum of viral …
people are infected per year globally. This is occurred by the diverse spectrum of viral …
Study of MDM2 as Prognostic Biomarker in Brain-LGG Cancer and Bioactive Phytochemicals Inhibit the p53-MDM2 Pathway: A Computational Drug Development …
An evaluation of the expression and predictive significance of the MDM2 gene in brain lower-
grade glioma (LGG) cancer was carried out using onco-informatics pipelines. Several …
grade glioma (LGG) cancer was carried out using onco-informatics pipelines. Several …
Molecular Dynamics Simulation and Pharmacoinformatic Integrated Analysis of Bioactive Phytochemicals from Azadirachta indica (Neem) to Treat Diabetes Mellitus
Diabetes mellitus is a chronic hormonal and metabolic disorder in which our body cannot
generate necessary insulin or does not act in response to it, accordingly, ensuing in …
generate necessary insulin or does not act in response to it, accordingly, ensuing in …
Review on the diverse biological effects of glabridin
J Zhang, X Wu, B Zhong, Q Liao, X Wang… - Drug Design …, 2023 - Taylor & Francis
Glabridin is a prenylated isoflavan from the roots of Glycyrrhiza glabra Linne and has posed
great impact on the areas of drug development and medicine, due to various biological …
great impact on the areas of drug development and medicine, due to various biological …
Investigating the anticancer potential of salvicine as a modulator of topoisomerase II and ROS signaling cascade
Salvicine is a new diterpenoid quinone substance from a natural source, specifically in a
Chinese herb. It has powerful growth-controlling abilities against a broad range of human …
Chinese herb. It has powerful growth-controlling abilities against a broad range of human …
Assessing anti oxidant, antidiabetic potential and GCMS profiling of ethanolic root bark extract of Zanthoxylum rhetsa (Roxb.) DC: Supported by in vitro, in vivo and in …
Zanthoxylum rhetsa (ZR) is used traditionally to manage a variety of ailments, including
diabetes. Oxidative stress may accelerate the diabetic condition. The available antidiabetic …
diabetes. Oxidative stress may accelerate the diabetic condition. The available antidiabetic …
[HTML][HTML] Exploring the therapeutic targets of stevioside in management of type 2 diabetes by network pharmacology and in-silico approach
Aims The main objective of the current study is to investigate the pathways and therapeutic
targets linked to stevioside in the management of T2D using computational approaches …
targets linked to stevioside in the management of T2D using computational approaches …