[HTML][HTML] Endocannabinoid-mediated control of synaptic transmission
M Kano, T Ohno-Shosaku… - Physiological …, 2009 - journals.physiology.org
The discovery of cannabinoid receptors and subsequent identification of their endogenous
ligands (endocannabinoids) in early 1990s have greatly accelerated research on …
ligands (endocannabinoids) in early 1990s have greatly accelerated research on …
Cannabis and psychosis/schizophrenia: human studies
The association between cannabis use and psychosis has long been recognized. Recent
advances in knowledge about cannabinoid receptor function have renewed interest in this …
advances in knowledge about cannabinoid receptor function have renewed interest in this …
Contributions of endocannabinoid signaling to psychiatric disorders in humans: genetic and biochemical evidence
The endocannabinoid signaling system is a widespread, neuromodulatory system in brain
and is also widely utilized in the periphery to modulate metabolic functions and the immune …
and is also widely utilized in the periphery to modulate metabolic functions and the immune …
Brain cannabinoid CB2 receptor in schizophrenia
BACKGROUND: Neural endocannabinoid function appears to be involved in schizophrenia.
Two endocannabinoid receptors, CB1 and CB2, are found in the brain and elsewhere in the …
Two endocannabinoid receptors, CB1 and CB2, are found in the brain and elsewhere in the …
Quantification of cerebral cannabinoid receptors subtype 1 (CB1) in healthy subjects and schizophrenia by the novel PET radioligand [11C] OMAR
Several studies have examined the link between the cannabinoid CB1 receptor and several
neuropsychiatric illnesses, including schizophrenia. As such, there is a need for in vivo …
neuropsychiatric illnesses, including schizophrenia. As such, there is a need for in vivo …
Cannabinoid receptor CNR1 expression and DNA methylation in human prefrontal cortex, hippocampus and caudate in brain development and schizophrenia
Beyond being one the most widely used psychoactive drugs in the world, cannabis has
been identified as an environmental risk factor for psychosis. Though the relationship …
been identified as an environmental risk factor for psychosis. Though the relationship …
The endocannabinoid system and psychiatric disorders
D Parolaro, N Realini, D Vigano, C Guidali… - Experimental …, 2010 - Elsevier
The present review summarizes the latest information on the role and the pharmacological
modulation of the endocannabinoid system in mood disorders and its potential implication in …
modulation of the endocannabinoid system in mood disorders and its potential implication in …
Role of cannabis and endocannabinoids in the genesis of schizophrenia
E Fernandez-Espejo, MP Viveros, L Núñez… - …, 2009 - Springer
Rationale Cannabis abuse and endocannabinoids are associated to schizophrenia.
Objectives It is important to discern the association between schizophrenia and exogenous …
Objectives It is important to discern the association between schizophrenia and exogenous …
CNR1 gene is associated with high neuroticism and low agreeableness and interacts with recent negative life events to predict current depressive symptoms
Abstract Cannabinoid receptor 1 (CB1) gene (CNR1) knockout mice are prone to develop
anhedonic and helpless behavior after chronic mild stress. In humans, the CB1 antagonist …
anhedonic and helpless behavior after chronic mild stress. In humans, the CB1 antagonist …
The cannabinoid receptor 1 associates with NMDA receptors to produce glutamatergic hypofunction: implications in psychosis and schizophrenia
P Sánchez-Blázquez, M Rodríguez-Muñoz… - Frontiers in …, 2014 - frontiersin.org
The endocannabinoid system is widespread throughout the central nervous system and its
type 1 receptor (CB1) plays a crucial role in preventing the neurotoxicity caused by …
type 1 receptor (CB1) plays a crucial role in preventing the neurotoxicity caused by …