Gamma oscillation is the synchronization with a frequency of 30–90 Hz of neural
oscillations, which are rhythmic electric processes of neuron groups in the brain. The …

Epileptogenesis in infants with tuberous sclerosis complex (TSC) is a gradual and dynamic
process, leading to early onset and difficult-to-treat seizures. Several cellular, molecular and …

Alterations in energy metabolism are associated with depression. However, the role of
glycolysis in the pathogenesis of depression and the underlying molecular mechanisms …

Diabetic patients receiving the antidiabetic drug metformin have been observed to exhibit a
lower prevalence of anxiety disorders, yet the precise mechanism behind this phenomenon …

The infiltration of immune cells is observed in the epileptogenic zone; however, the
relationship between epilepsy and regulatory T cells (Tregs) remains only partially …

Neddylation, a type of protein post-translational modification that links the ubiquitin-like
protein NEDD8 to substrate proteins, can be involved in various significant cellular …

The precise control of the nervous system function under the vitality of synapses is extremely
critical. Efforts have been taken to explore the underlying cellular and molecular …

Parvalbumin interneurons belong to the major types of GABAergic interneurons. Although
the distribution and pathological alterations of parvalbumin interneuron somata have been …

Cardiac maturation is crucial for postnatal cardiac development and is increasingly known to
be regulated by a series of transcription factors. However, post-translational mechanisms …

Background Autosomal dominant lateral temporal epilepsy (ADLTE) is an inherited
syndrome caused by mutations in the leucine-rich glioma inactivated 1 (LGI1) gene. It is …