Biosynthesis of GPI-anchored proteins: special emphasis on GPI lipid remodeling.
T Kinoshita, M Fujita - Journal of lipid research, 2015 - europepmc.org
Glycosylphosphatidylinositols (GPIs) act as membrane anchors of many eukaryotic cell
surface proteins. GPIs in various organisms have a common backbone consisting of …
surface proteins. GPIs in various organisms have a common backbone consisting of …
Fibrillar collagens
Fibrillar collagens (types I, II, III, V, XI, XXIV and XXVII) constitute a sub-group within the
collagen family (of which there are 28 types in humans) whose functions are to provide three …
collagen family (of which there are 28 types in humans) whose functions are to provide three …
A marine microbiome antifungal targets urgent-threat drug-resistant fungi
New antifungal drugs are urgently needed to address the emergence and transcontinental
spread of fungal infectious diseases, such as pandrug-resistant Candida auris. Leveraging …
spread of fungal infectious diseases, such as pandrug-resistant Candida auris. Leveraging …
Seipin and the membrane-sha** protein Pex30 cooperate in organelle budding from the endoplasmic reticulum
S Wang, FZ Idrissi, M Hermansson, A Grippa… - Nature …, 2018 - nature.com
Lipid droplets (LDs) and peroxisomes are ubiquitous organelles with central roles in
eukaryotic cells. Although the mechanisms involved in biogenesis of these organelles …
eukaryotic cells. Although the mechanisms involved in biogenesis of these organelles …
Posttranslational regulation of HMG CoA reductase, the rate-limiting enzyme in synthesis of cholesterol
MM Schumacher… - Annual review of …, 2021 - annualreviews.org
The polytopic, endoplasmic reticulum (ER) membrane protein 3-hydroxy-3-methylglutaryl
coenzyme A (HMG CoA) reductase produces mevalonate, the key intermediate in the …
coenzyme A (HMG CoA) reductase produces mevalonate, the key intermediate in the …
Upregulation of ribosome complexes at the blood-brain barrier in Alzheimer's disease patients
M Suzuki, K Tezuka, T Handa, R Sato… - Journal of Cerebral …, 2022 - journals.sagepub.com
The cerebrovascular-specific molecular mechanism in Alzheimer's disease (AD) was
investigated by employing comprehensive and accurate quantitative proteomics. Highly …
investigated by employing comprehensive and accurate quantitative proteomics. Highly …
Mechanisms regulating protein localization
Cellular functions are dictated by protein content and activity. There are numerous strategies
to regulate proteins varying from modulating gene expression to post‐translational …
to regulate proteins varying from modulating gene expression to post‐translational …
The pathway of collagen secretion
COPII vesicles mediate export of secretory cargo from the endoplasmic reticulum (ER).
However, a standard COPII vesicle with a diameter of 60–90 nm is too small to export …
However, a standard COPII vesicle with a diameter of 60–90 nm is too small to export …
[HTML][HTML] A CYP78As–small grain4–coat protein complex Ⅱ pathway promotes grain size in rice
C Zhou, Q Lin, Y Ren, J Lan, R Miao, M Feng… - The Plant …, 2023 - ncbi.nlm.nih.gov
Abstract CYP78A, a cytochrome P450 subfamily that includes rice (Oryza sativa L.) BIG
GRAIN2 (BG2, CYP78A13) and Arabidopsis thaliana KLUH (KLU, CYP78A5), generate an …
GRAIN2 (BG2, CYP78A13) and Arabidopsis thaliana KLUH (KLU, CYP78A5), generate an …
[HTML][HTML] Ultrastructure of the replication sites of positive-strand RNA viruses
C Harak, V Lohmann - Virology, 2015 - Elsevier
Positive strand RNA viruses replicate in the cytoplasm of infected cells and induce
intracellular membranous compartments harboring the sites of viral RNA synthesis. These …
intracellular membranous compartments harboring the sites of viral RNA synthesis. These …