[HTML][HTML] Drug resistance in liver flukes

I Fairweather, GP Brennan, REB Hanna… - International Journal for …, 2020 - Elsevier
Liver flukes include Fasciola hepatica, Fasciola gigantica, Clonorchis sinensis, Opisthorchis
spp., Fascioloides magna, Gigantocotyle explanatum and Dicrocoelium spp. The two main …

Metal compounds against neglected tropical diseases

YC Ong, S Roy, PC Andrews, G Gasser - Chemical reviews, 2018 - ACS Publications
Many first-line treatments for neglected tropical diseases identified by the World Health
Organization (WHO) are limited by one or more of the following: the development of drug …

Immunoinformatics Design of Multi-Epitope Peptide-Based Vaccine Against Schistosoma mansoni Using Transmembrane Proteins as a Target

RCO Sanches, S Tiwari, LCG Ferreira… - Frontiers in …, 2021 - frontiersin.org
Schistosomiasis remains a serious health issue nowadays for an estimated one billion
people in 79 countries around the world. Great efforts have been made to identify good …

Asian schistosomiasis: current status and prospects for control leading to elimination

CA Gordon, J Kurscheid, GM Williams… - Tropical medicine and …, 2019 - mdpi.com
Schistosomiasis is an infectious disease caused by helminth parasites of the genus
Schistosoma. Worldwide, an estimated 250 million people are infected with these parasites …

Ferrocene derivatives as anti-infective agents

BS Ludwig, JDG Correia, FE Kühn - Coordination Chemistry Reviews, 2019 - Elsevier
Infectious diseases like malaria, tuberculosis or HIV are among the leading causes of death
worldwide according to WHO estimations. Nevertheless, the fight against infectious diseases …

Urogenital schistosomiasis—history, pathogenesis, and bladder cancer

LL Santos, J Santos, MJ Gouveia, C Bernardo… - Journal of Clinical …, 2021 - mdpi.com
Schistosomiasis is the most important helminthiasis worldwide in terms of morbidity and
mortality. Most of the infections occurs in Africa, which about two thirds are caused by …

Life cycle maintenance and drug-sensitivity assays for early drug discovery in Schistosoma mansoni

FC Lombardo, V Pasche, G Panic, Y Endriss… - Nature Protocols, 2019 - nature.com
Drug discovery for schistosomiasis is still limited to a handful of academic laboratories
worldwide, with only a few novel antischistosomal lead compounds being actively …

The pipeline for drugs for control and elimination of neglected tropical diseases: 1. Anti-infective drugs for regulatory registration

KM Pfarr, AK Krome, I Al-Obaidi, H Batchelor… - Parasites & …, 2023 - Springer
Abstract The World Health Organization 'Ending the neglect to attain the Sustainable
Development Goals: A road map for neglected tropical diseases 2021–2030'outlines the …

Promising technologies in the field of helminth vaccines

DJ Perera, M Ndao - Frontiers in immunology, 2021 - frontiersin.org
Helminths contribute a larger global burden of disease than both malaria and tuberculosis.
These eukaryotes have caused human infections since before our earliest recorded history …

A critical review on human malaria and schistosomiasis vaccines: current state, recent advancements, and developments

AJ Siddiqui, J Bhardwaj, J Saxena, S Jahan, M Snoussi… - Vaccines, 2023 - mdpi.com
Malaria and schistosomiasis are two major parasitic diseases that remain leading causes of
morbidity and mortality worldwide. Co-infections of these two parasites are common in the …