Skin wound healing: normal macrophage function and macrophage dysfunction in diabetic wounds

SM Aitcheson, FD Frentiu, SE Hurn, K Edwards… - Molecules, 2021 - mdpi.com
Macrophages play a prominent role in wound healing. In the early stages, they promote
inflammation and remove pathogens, wound debris, and cells that have apoptosed. Later in …

Innovative functional biomaterials as therapeutic wound dressings for chronic diabetic foot ulcers

J Da Silva, EC Leal, E Carvalho, EA Silva - International Journal of …, 2023 - mdpi.com
The imbalance of local and systemic factors in individuals with diabetes mellitus (DM)
delays, or even interrupts, the highly complex and dynamic process of wound healing …

[HTML][HTML] Bioactive antimicrobial peptides as therapeutic agents for infected diabetic foot ulcers

J Da Silva, EC Leal, E Carvalho - Biomolecules, 2021 - mdpi.com
Diabetic foot ulcer (DFU) is a devastating complication, affecting around 15% of diabetic
patients and representing a leading cause of non-traumatic amputations. Notably, the risk of …

Tackling chronic wound healing using nanomaterials: advancements, challenges, and future perspectives

G Yaşayan, O Nejati, AF Ceylan, Ç Karasu… - Applied Materials …, 2023 - Elsevier
Chronic wounds are known as one of the biggest health challenges, especially in the case
of diabetes patients, which annually engages millions of patients, and its management …

Skin immunity in wound healing and cancer

A Jakovija, T Chtanova - Frontiers in Immunology, 2023 - frontiersin.org
The skin is the body's largest organ. It serves as a barrier to pathogen entry and the first site
of immune defense. In the event of a skin injury, a cascade of events including inflammation …

Candida albicans and Antifungal Peptides

CG Freitas, MS Felipe - Infectious Diseases and Therapy, 2023 - Springer
Candida albicans, a ubiquitous opportunistic fungal pathogen, plays a pivotal role in human
health and disease. As a commensal organism, it normally resides harmlessly within the …

Antimicrobial-wound healing peptides: Dual-function molecules for the treatment of skin injuries

GS de Souza, L de Jesus Sonego, ACS Mundim… - Peptides, 2022 - Elsevier
Chronic non-healing wounds caused by microbial infections extend the necessity for
hospital care and constitute a public health problem and a great financial burden. Classic …

Biopolymer-based wound dressings with biochemical cues for cell-instructive wound repair

V Singh, T Marimuthu, MM Makatini, YE Choonara - Polymers, 2022 - mdpi.com
Regenerative medicine is an active research sphere that focuses on the repair,
regeneration, and replacement of damaged tissues and organs. A plethora of innovative …

Unraveling the New Perspectives on Antimicrobial Hydrogels: State-of-the-Art and Translational Applications

MA Ortega, D De Leon-Oliva, DL Boaru… - Gels, 2023 - mdpi.com
The growing impact of infections and the rapid emergence of antibiotic resistance represent
a public health concern worldwide. The exponential development in the field of biomaterials …

Advances in Transdermal Delivery of Antimicrobial Peptides for Wound Management: Biomaterial-Based Approaches and Future Perspectives

SO Firdous, MMH Sagor, MT Arafat - ACS Applied Bio Materials, 2023 - ACS Publications
Antimicrobial peptides (AMPs), distinguished by their cationic and amphiphilic nature,
represent a critical frontier in the battle against antimicrobial resistance due to their potent …