Nonequilibrium thermodynamics of thiol/disulfide redox systems: a perspective on redox systems biology
Understanding the dynamics of redox elements in biologic systems remains a major
challenge for redox signaling and oxidative stress research. Central redox elements include …
challenge for redox signaling and oxidative stress research. Central redox elements include …
Biochemical systems theory: a review
EO Voit - International Scholarly Research Notices, 2013 - Wiley Online Library
Biochemical systems theory (BST) is the foundation for a set of analytical andmodeling tools
that facilitate the analysis of dynamic biological systems. This paper depicts major …
that facilitate the analysis of dynamic biological systems. This paper depicts major …
Recasting nonlinear differential equations as S-systems: a canonical nonlinear form
An enormous variety of nonlinear differential equations and functions have been recast
exactly in the canonical form called an S-system. This is a system of nonlinear ordinary …
exactly in the canonical form called an S-system. This is a system of nonlinear ordinary …
Decoupling dynamical systems for pathway identification from metabolic profiles
Rationale: Modern molecular biology is generating data of unprecedented quantity and
quality. Particularly exciting for biochemical pathway modeling and proteomics are …
quality. Particularly exciting for biochemical pathway modeling and proteomics are …
Design principles for elementary gene circuits: Elements, methods, and examples
MA Savageau - Chaos: An Interdisciplinary Journal of Nonlinear …, 2001 - pubs.aip.org
The gene circuitry of an organism connects its gene set genome to its patterns of phenotypic
expression. The genotype is determined by the information encoded in the DNA sequence …
expression. The genotype is determined by the information encoded in the DNA sequence …
Biochemical systems theory and metabolic control theory: 1. Fundamental similarities and differences
Abstract Biochemical Systems Theory (BST) was developed in the late 1960s to explicate
the integrated behavior of intact biochemical systems—specific dynamic behavior as well as …
the integrated behavior of intact biochemical systems—specific dynamic behavior as well as …
[КНИГА][B] Enzyme kinetics: from diastase to multi-enzyme systems
AR Schulz - 1994 - books.google.com
This text covers the field of steady-state kinetics from basic principles to the control of the
multi-enzyme systems which constitute metabolic pathways. Emphasis is placed on the …
multi-enzyme systems which constitute metabolic pathways. Emphasis is placed on the …
Development of fractal kinetic theory for enzyme-catalysed reactions and implications for the design of biochemical pathways
MA Savageau - Biosystems, 1998 - Elsevier
Recent evidence has shown that elementary bimolecular reactions under dimensionally-
restricted conditions, such as those that might occur within cells when reactions are confined …
restricted conditions, such as those that might occur within cells when reactions are confined …
Introduction to S-systems and the underlying power-law formalism
MA Savageau - Mathematical and Computer Modelling, 1988 - Elsevier
A novel approach to the development of an appropriate formalism for representing
organizationally complex systems began in the mid 1960's with a search for a general …
organizationally complex systems began in the mid 1960's with a search for a general …
The best models of metabolism
EO Voit - Wiley Interdisciplinary Reviews: Systems Biology and …, 2017 - Wiley Online Library
Biochemical systems are among of the oldest application areas of mathematical modeling.
Spanning a time period of over one hundred years, the repertoire of options for structuring a …
Spanning a time period of over one hundred years, the repertoire of options for structuring a …