It is widely accepted that nine hallmarks—including mitochondrial dysfunction, epigenetic
alterations, and loss of proteostasis—exist that describe the cellular aging process. Adding …

Animal experimentation is limited by unethical procedures, time-consuming protocols, and
high cost. Thus, the development of innovative approaches for disease treatment based on …

Astragalus polysaccharide (APS) is a notable bioactive component of Astragalus
membranaceus and has been extensively investigated for its pharmacological activities …

Little is known about the metabolic basis of life-history trade-offs but lipid stores seem to play
a pivotal role. During reproduction, an energetically highly costly process, animals mobilize …

Sex differences in whole-body fat storage exist in many species. For example, Drosophila
females store more fat than males. Yet, the mechanisms underlying this sex difference in fat …

Several studies have been published introducing Drosophila melanogaster as a research
model to investigate the effects of high-calorie diets on metabolic dysfunctions. However …

The insect farming sector is expanding, but knowledge of insect welfare is still limited. This
article aims to optimize the dietary regime for “black soldier fly”(Hermetia illucens L., BSF) …

Phenotypic trade-offs are inevitable in nature, but the mechanisms driving them are poorly
understood. Movement and oxygen are essential to all animals, and as such, the common …

The model organism Drosophila melanogaster was increasingly applied in nutrition
research in recent years. A range of methods are available for the phenoty** of D …

In mammals, energy homeostasis is regulated by the antagonistic action of hormones insulin
and glucagon. However, in contrast to the highly conserved insulin, glucagon is absent in …