Amyloid or amyloid-like fibrils represent a general class of nanomaterials that can be formed
from many different peptides and proteins. Although these structures have an important role …

Proteins of the intermediate filament (IF) supergene family are ubiquitous structural
components that comprise, in a cell type–specific manner, the cytoskeleton proper in animal …

Vimentin is used widely as a marker of the epithelial to mesenchymal transitions (EMTs) that
take place during embryogenesis and metastasis, yet the functional implications of the …

Intermediate filaments (IFs) constitute a major structural element of animal cells. They build
two distinct systems, one in the nucleus and one in the cytoplasm. In both cases, their major …

The epithelial-mesenchymal transition (EMT) is intrinsically linked to alterations of the
intracellular cytoskeleton and the extracellular matrix. After EMT, cells acquire an elongated …

Intermediate filaments (IFs) are one of the three major elements of the cytoskeleton. Their
stability, intrinsic mechanical properties, and cell type–specific expression patterns …

Mammalian cells frequently migrate through tight spaces during normal embryogenesis,
wound healing, diapedesis, or in pathological situations such as metastasis. Nuclear size …

All cells sense and respond to various mechanical forces in and mechanical properties of
their environment. To respond appropriately, cells must be able to sense the location …

Metastasis is a complicated, multistep process that is responsible for over 90% of cancer-
related death. Metastatic disease or the movement of cancer cells from one site to another …

Intermediate filaments (IFs) are integral components of the cytoskeleton. They provide cells
with tissue-specific mechanical properties and are involved in numerous cellular processes …