Studying within-species variation has traditionally been limited to culturable bacterial
isolates and low-resolution microbial community fingerprinting. Metagenomic sequencing …

Infection of the colon with the Gram-positive bacterium Clostridium difficile is potentially life
threatening, especially in elderly people and in patients who have dysbiosis of the gut …

Clostridium difficile is a bacterial pathogen that is the leading cause of nosocomial antibiotic-
associated diarrhea and pseudomembranous colitis worldwide. The incidence, severity …

Clostridium difficile infection (CDI) continues to affect patients in hospitals and communities
worldwide. The spectrum of clinical disease ranges from mild diarrhoea to toxic megacolon …

Globally, the ESKAPE pathogens (Enterococcus faecium, Staphylococcus aureus, Klebsiella
pneumoniae, Acinetobacter baumannii, Pseudomonas aeruginosa, and Enterobacter …

Clostridium difficile infection (CDI) has significant clinical impact especially on the elderly
and/or immunocompromised patients. The pathogenicity of Clostridium difficile is mainly …

Importance Clostridium difficileis the most common cause of health care–associated
infection in US hospitals. Recurrence occurs in 25% to 30% of patients. Objective To …

Clostridium difficile infection (CDI) is the leading cause of antimicrobial and health care-
associated diarrhea in humans, presenting a significant burden to global health care …

Abstract Background The epidemiology of Clostridium difficile infection (CDI) has changed
over the past decades with the emergence of highly virulent strains. The role of …

Clostridium difficile is the most frequent cause of nosocomial antibiotic-associated diarrhea.
The incidence of C. difficile infection (CDI) has been rising worldwide with subsequent …