Periodontitis is a chronic inflammatory disease of the gums. The incidence of periodontitis is
increasing all over the world. In patients with periodontitis, there is gradual destruction of the …

Phosphatase and tensin homolog (PTEN), phosphatidylinositol 3-kinase (PI3K), and protein
kinase B (Akt) signaling pathways contribute to the development of several cancers …

Exosomal long noncoding RNAs (lncRNA) derived from cancer cells are implicated in
various processes, including cancer cell proliferation, metastasis, and immunomodulation …

Galectin-9 (Gal-9) is a tandem-repeat galectin with diverse roles in immune homeostasis,
inflammation, malignancy, and autoimmune diseases. In cancer, Gal-9 displays variable …

Multiple myeloma (MM) is a malignancy of plasma cells in the bone marrow and is
characterized by the clonal proliferation of B-cells producing defective monoclonal …

Multiple myeloma (MM) is a clinical disorder characterized by aberrant plasma cell growth in
the bone marrow microenvironment. Globally, the prevalence of MM has been steadily …

Multiple myeloma (MM) is an exceptionally complicated and heterogeneous disease that is
caused by the abnormal proliferation of malignant monoclonal plasma cells initiated in the …

Herein, we study the assembling of a drug delivery nanocarrier through reactive molecular
dynamics simulations based on an appropriately tuned force field. First, we focus on the …

Simple Summary According to the literature, 35–71% of multiple myeloma patients have
nutritional disorders. In the development of cachexia and malnutrition, the inflammatory …

Aims This study aimed to investigate the effect and mechanism of methylcrotonyl-CoA
carboxylase subunit 1 (MCCA) on multidrug resistance in multiple myeloma (MM). Materials …