Emerging Transcriptional and Genomic Mechanisms Mediating Carbapenem and Polymyxin Resistance in Enterobacteriaceae: a Systematic Review of Current …

M Mmatli, NM Mbelle, NE Maningi, J Osei Sekyere - MSystems, 2020 - Am Soc Microbiol
The spread of carbapenem-and polymyxin-resistant Enterobacteriaceae poses a significant
threat to public health, challenging clinicians worldwide with limited therapeutic options. This …

Sales of antibiotics and hydroxychloroquine in India during the COVID-19 epidemic: An interrupted time series analysis

G Sulis, B Batomen, A Kotwani, M Pai, S Gandra - PLoS medicine, 2021 - journals.plos.org
Background We assessed the impact of the coronavirus disease 2019 (COVID-19) epidemic
in India on the consumption of antibiotics and hydroxychloroquine (HCQ) in the private …

An Intertwined Network of Regulation Controls Membrane Permeability Including Drug Influx and Efflux in Enterobacteriaceae

A Ferrand, J Vergalli, JM Pagès, A Davin-Regli - Microorganisms, 2020 - mdpi.com
The transport of small molecules across membranes is a pivotal step for controlling the drug
concentration into the bacterial cell and it efficiently contributes to the antibiotic susceptibility …

Antibiotic overuse in the primary health care setting: a secondary data analysis of standardised patient studies from India, China and Kenya

G Sulis, B Daniels, A Kwan, S Gandra, A Daftary… - BMJ Global …, 2020 - gh.bmj.com
Introduction Determining whether antibiotic prescriptions are inappropriate requires
knowledge of patients' underlying conditions. In low-income and middle-income countries …

Characteristics of diarrheagenic Escherichia coli pathotypes among children under the age of 10 years with acute diarrhea

G Shahbazi, MA Rezaee, F Nikkhahi, S Ebrahimzadeh… - Gene Reports, 2021 - Elsevier
Introduction This study was aimed to evaluate the prevalence of diarrheagenic Escherichia
coli (DEC) and ESBL genes in the children with gastroenteritis and to explore the …

First report of a blaNDM-5-carrying Escherichia coli sequence type 12 isolated from a dog with pyometra in Japan

K Harada, T Miyamoto, M Sugiyama, T Asai - Journal of Infection and …, 2024 - Elsevier
Carbapenemase-producing Enterobacterales (CPE) are a serious concern in human clinical
settings. Companion animal–origin CPE have been only rarely identified in several …

A systematic sco** review of faropenem and other oral penems: treatment of Enterobacterales infections, development of resistance and cross-resistance to …

S Gandra, S Takahashi, FS Mitrani-Gold… - JAC-Antimicrobial …, 2022 - academic.oup.com
Background Antimicrobial resistance is an urgent global healthcare concern. Beyond
carbapenems as broad-spectrum, often 'last resort'antibiotics, oral penem antibiotics …

β-Lactam antibiotics

JF Fisher, Y Qian, S Mobashery - Medicinal Chemistry of Chemotherapeutic …, 2023 - Elsevier
The ability to control bacterial infection transformed the practice of medicine. Of the first
antibacterial compounds isolated from Nature nearly a century ago—the gramicidins, the …

Oral Faropenem Sodium—Implications for Antimicrobial Resistance and Treatment Effectiveness

D Dharmapalan, SJ Chandy - Indian pediatrics, 2022 - Springer
Rising antimicrobial resistance (AMR) is causing therapeutic failures with antibiotics.
Inappropriate use is a contributing factor. One such antibiotic on the radar is faropenem, a …

[PDF][PDF] JAC-Antimicrobial Resistance

P Sanders, D Mevius, K Veldman, I van Geijlswijk… - 2021 - edepot.wur.nl
Objectives: To explore the effects of using different indicators to quantify antimicrobial usage
(AMU) in livestock and compare outcomes with antimicrobial resistance (AMR) data …