Role of ANO1 in tumors and tumor immunity
H Li, Z Yu, H Wang, N Wang, X Sun, S Yang… - Journal of Cancer …, 2022 - Springer
Dysregulation of gene amplification, cell-signaling–pathway transduction, epigenetic and
transcriptional regulation, and protein interactions drives tumor-cell proliferation and …
transcriptional regulation, and protein interactions drives tumor-cell proliferation and …
Bioinformatic characterization of the Anoctamin Superfamily of Ca2+-activated ion channels and lipid scramblases
Our laboratory has developed bioinformatic strategies for identifying distant phylogenetic
relationships and characterizing families and superfamilies of transport proteins. Results …
relationships and characterizing families and superfamilies of transport proteins. Results …
MCM2 is a therapeutic target of lovastatin in human non-small cell lung carcinomas
X Zhang, Y Teng, F Yang, M Wang… - Oncology …, 2015 - spandidos-publications.com
Human non-small cell lung carcinoma (NSCLC) is one of the most common cancer
worldwide. In previous studies, lovastatin, acting as an inhibitor of 3-hydroxy‑3 …
worldwide. In previous studies, lovastatin, acting as an inhibitor of 3-hydroxy‑3 …
TRPC1 regulates calcium‐activated chloride channels in salivary gland cells
Calcium‐activated chloride channel (CaCC) plays an important role in modulating epithelial
secretion. It has been suggested that in salivary tissues, sustained fluid secretion is …
secretion. It has been suggested that in salivary tissues, sustained fluid secretion is …
Role of transportome in the gills of Chinese mitten crabs in response to salinity change: A meta-analysis of rna-seq datasets
Simple Summary Eriocheir sinensis is a freshwater crab and is considered as one of the
most important cost-effective species for freshwater aquaculture. E. sinensis can grow in …
most important cost-effective species for freshwater aquaculture. E. sinensis can grow in …
Identification of resveratrol, an herbal compound, as an activator of the calcium-activated chloride channel, TMEM16A
Calcium-activated chloride channels (CaCCs) play vital roles in a variety of physiological
processes. Dysfunction of the CaCCs is implicated in many diseases. Drug discovery …
processes. Dysfunction of the CaCCs is implicated in many diseases. Drug discovery …
[HTML][HTML] Anoctamin 5 regulates the cell cycle and affects prognosis in gastric cancer
T Fukami, A Shiozaki, T Kosuga, M Kudou… - World Journal of …, 2022 - ncbi.nlm.nih.gov
BACKGROUND Anoctamin 5 (ANO5)/transmembrane protein 16E belongs to the
ANO/transmembrane protein 16 anion channel family. ANOs comprise a family of plasma …
ANO/transmembrane protein 16 anion channel family. ANOs comprise a family of plasma …
Ano1 as a novel drug target
A Bill, LA Gaither - Transporters as Drug Targets, 2017 - Wiley Online Library
Anoctamin 1 (ANO1 or TMEM16A) is now widely accepted to be a major calcium‐activated
chloride (Cl‐) channel (CaCC) in a wide variety of tissues including the secretory epithelia …
chloride (Cl‐) channel (CaCC) in a wide variety of tissues including the secretory epithelia …
β2 adrenoceptor signaling regulates ion transport in 16HBE14o‐ human airway epithelial cells
RG Zhang, CY Yip, K Pan, M Cai… - Journal of Cellular …, 2020 - Wiley Online Library
We investigated the regulation of Cl− secretion by adrenoceptors in polarized 16HBE14o‐
human bronchial epithelial cells. Treatment with the nonselective β adrenoceptor agonist …
human bronchial epithelial cells. Treatment with the nonselective β adrenoceptor agonist …
Soft‐wall ion transfer channel accurately predicts sterically hindered ion channel permeability
We provide a simple and systematic computational model to study ion channel permeability
using density functional theory. While existing permeability models with a hard‐wall steric …
using density functional theory. While existing permeability models with a hard‐wall steric …