Transformer architecture and attention mechanisms in genome data analysis: a comprehensive review

SR Choi, M Lee - Biology, 2023 - mdpi.com
Simple Summary The rapidly advancing field of deep learning, specifically transformer-
based architectures and attention mechanisms, has found substantial applicability in …

Accurately identifying hemagglutinin using sequence information and machine learning methods

X Zou, L Ren, P Cai, Y Zhang, H Ding, K Deng… - Frontiers in …, 2023 - frontiersin.org
Introduction Hemagglutinin (HA) is responsible for facilitating viral entry and infection by
promoting the fusion between the host membrane and the virus. Given its significance in the …

A first computational frame for recognizing heparin-binding protein

W Zhu, SS Yuan, J Li, CB Huang, H Lin, B Liao - Diagnostics, 2023 - mdpi.com
Heparin-binding protein (HBP) is a cationic antibacterial protein derived from multinuclear
neutrophils and an important biomarker of infectious diseases. The correct identification of …

Advances in the roles and mechanisms of mesenchymal stem cell derived microRNAs on periodontal tissue regeneration

J Zhang, L Chen, J Yu, W Tian, S Guo - Stem Cell Research & Therapy, 2024 - Springer
Periodontitis is one of the most prevalent oral diseases leading to tooth loss in adults, and is
characterized by the destruction of periodontal supporting structures. Traditional therapies …

H2Opred: a robust and efficient hybrid deep learning model for predicting 2'-O-methylation sites in human RNA

NT Pham, R Rakkiyapan, J Park, A Malik… - Briefings in …, 2024 - academic.oup.com
O-methylation (2OM) is the most common post-transcriptional modification of RNA. It plays a
crucial role in RNA splicing, RNA stability and innate immunity. Despite advances in high …

Advancing the accuracy of SARS-CoV-2 phosphorylation site detection via meta-learning approach

NT Pham, LT Phan, J Seo, Y Kim, M Song… - Briefings in …, 2024 - academic.oup.com
The worldwide appearance of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-
2) has generated significant concern and posed a considerable challenge to global health …

iPADD: a computational tool for predicting potential antidiabetic drugs using machine learning algorithms

XW Liu, TY Shi, D Gao, CY Ma, H Lin… - Journal of Chemical …, 2023 - ACS Publications
Diabetes mellitus is a chronic metabolic disease, which causes an imbalance in blood
glucose homeostasis and further leads to severe complications. With the increasing …

DeepLocRNA: an interpretable deep learning model for predicting RNA subcellular localization with domain-specific transfer-learning

J Wang, M Horlacher, L Cheng, O Winther - Bioinformatics, 2024 - academic.oup.com
Motivation Accurate prediction of RNA subcellular localization plays an important role in
understanding cellular processes and functions. Although post-transcriptional processes are …

i2OM: Toward a better prediction of 2′-O-methylation in human RNA

YH Yang, CY Ma, D Gao, XW Liu, SS Yuan… - International Journal of …, 2023 - Elsevier
O-methylation (2OM) is an omnipresent post-transcriptional modification in RNAs. It is
important for the regulation of RNA stability, mRNA splicing and translation, as well as innate …

GeneAI 3.0: powerful, novel, generalized hybrid and ensemble deep learning frameworks for miRNA species classification of stationary patterns from nucleotides

J Singh, NN Khanna, RK Rout, N Singh, JR Laird… - Scientific reports, 2024 - nature.com
Due to the intricate relationship between the small non-coding ribonucleic acid (miRNA)
sequences, the classification of miRNA species, namely Human, Gorilla, Rat, and Mouse is …