Plants metabolites: possibility of natural therapeutics against the COVID-19 pandemic

FR Bhuiyan, S Howlader, T Raihan, M Hasan - Frontiers in medicine, 2020 - frontiersin.org
COVID-19, a disease induced by SARS-CoV-2 (Severe Acute Respiratory Syndrome
Coronavirus-2), has been the cause of a worldwide pandemic. Though extensive research …

Propolis: An update on its chemistry and pharmacological applications

R Hossain, C Quispe, RA Khan, ASM Saikat, P Ray… - Chinese medicine, 2022 - Springer
Propolis, a resinous substance produced by honeybees from various plant sources, has
been used for thousands of years in traditional medicine for several purposes all over the …

Current prevention of COVID-19: natural products and herbal medicine

J Huang, G Tao, J Liu, J Cai, Z Huang… - Frontiers in …, 2020 - frontiersin.org
Starting from December 2019, novel coronavirus disease 2019 (COVID-19) pandemic has
caused tremendous economic loss and unprecedented health crisis across the globe. While …

Propolis, bee honey, and their components protect against coronavirus disease 2019 (COVID-19): A review of in silico, in vitro, and clinical studies

AM Ali, H Kunugi - Molecules, 2021 - mdpi.com
Despite the virulence and high fatality of coronavirus disease 2019 (COVID-19), no specific
antiviral treatment exists until the current moment. Natural agents with immune-promoting …

[HTML][HTML] Efficacy of Brazilian green propolis (EPP-AF®) as an adjunct treatment for hospitalized COVID-19 patients: A randomized, controlled clinical trial

MAD Silveira, D De Jong, AA Berretta… - Biomedicine & …, 2021 - Elsevier
Background Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) promotes
challenging immune and inflammatory phenomena. Though various therapeutic possibilities …

Contributions of human ACE2 and TMPRSS2 in determining host–pathogen interaction of COVID-19

S Senapati, P Banerjee, S Bhagavatula… - Journal of genetics, 2021 - Springer
Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) infection is at present an
emerging global public health crisis. Angiotensin converting enzyme 2 (ACE2) and trans …

Propolis antiviral and immunomodulatory activity: a review and perspectives for COVID-19 treatment

N Ripari, AA Sartori, M da Silva Honorio… - Journal of Pharmacy …, 2021 - academic.oup.com
Objectives Viral outbreaks are a frequent concern for humans. A great variety of drugs has
been used to treat viral diseases, which are not always safe and effective and may induce …

Withanone from Withania somnifera Attenuates SARS-CoV-2 RBD and Host ACE2 Interactions to Rescue Spike Protein Induced Pathologies in Humanized Zebrafish …

A Balkrishna, S Pokhrel, H Singh, M Joshi… - Drug design …, 2021 - Taylor & Francis
Purpose SARS-CoV-2 engages human ACE2 through its spike (S) protein receptor binding
domain (RBD) to enter the host cell. Recent computational studies have reported that …

Anti-viral and immunomodulatory properties of propolis: Chemical diversity, pharmacological properties, preclinical and clinical applications, and in silico potential …

N Yosri, AA Abd El-Wahed, R Ghonaim, OM Khattab… - Foods, 2021 - mdpi.com
Propolis, a resin produced by honeybees, has long been used as a dietary supplement and
folk remedy, and more recent preclinical investigations have demonstrated a large spectrum …

[HTML][HTML] Withania somnifera (L.) Dunal: opportunity for clinical repurposing in COVID-19 management

A Saggam, K Limgaokar, S Borse… - Frontiers in …, 2021 - frontiersin.org
As the COVID-19 pandemic is progressing, the therapeutic gaps in conventional
management have highlighted the need for the integration of traditional knowledge systems …