In the last decades, a number of infectious viruses have emerged from wildlife or re-
emerged, generating serious threats to the global health and to the economy worldwide …

Recent developments in the use of viruses as vaccine vectors have been facilitated by a
better understanding of viral biology. Advances occur as we gain greater insight into the …

Antigenic diversity has posed a critical barrier to vaccine development against the
pathogenic blood-stage infection of the human malaria parasite Plasmodium falciparum. To …

Abstract The Middle East respiratory syndrome coronavirus (MERS-CoV) has infected more
than 1900 humans, since 2012. The syndrome ranges from asymptomatic and mild cases to …

Vaccines could be a crucial component of efforts to eradicate malaria. Current attempts to
develop malaria vaccines are primarily focused on Plasmodium falciparum and are directed …

Current vaccine strategies against the asexual blood stage of Plasmodium falciparum are
mostly focused on well-studied merozoite antigens that induce immune responses after …

The development of a highly effective vaccine remains a key strategic goal to aid the control
and eventual eradication of Plasmodium falciparum malaria. In recent years, the reticulocyte …

The induction of cellular immunity, in conjunction with antibodies, may be essential for
vaccines to protect against blood-stage infection with the human malaria parasite …

Adenovirus (Ad) vectors were initially developed for treatment of genetic diseases. Their
usefulness for permanent gene replacement was limited by their high immunogenicity …

Despite advancements in immunotherapeutic approaches, influenza continues to cause
severe illness, particularly among immunocompromised individuals, young children, and …