The in vivo fate of polymeric micelles
This review aims to provide a systemic analysis of the in vivo, as well as subcellular, fate of
polymeric micelles (PMs), starting from the entry of PMs into the body. Few PMs are able to …
polymeric micelles (PMs), starting from the entry of PMs into the body. Few PMs are able to …
Physiology and physical chemistry of bile acids
Bile acids (BAs) are facial amphiphiles synthesized in the body of all vertebrates. They
undergo the enterohepatic circulation: they are produced in the liver, stored in the …
undergo the enterohepatic circulation: they are produced in the liver, stored in the …
Bilosomes as effective delivery systems to improve the gastrointestinal stability and bioavailability of epigallocatechin gallate (EGCG)
L Wang, X Huang, H **g, C Ma, H Wang - Food research international, 2021 - Elsevier
Epigallocatechin gallate (EGCG) has a variety of biological activities, but exhibits poor
stability and low bioavailability. In this study, EGCG bilosome was prepared and …
stability and low bioavailability. In this study, EGCG bilosome was prepared and …
Self-assembly of bile salts and their mixed aggregates as building blocks for smart aggregates
The present communication offers a comprehensive overview of the self-assembly of bile
salts emphasizing their mixed smart aggregates with a variety of amphiphiles. Using an …
salts emphasizing their mixed smart aggregates with a variety of amphiphiles. Using an …
[HTML][HTML] Solubilization techniques used for poorly water-soluble drugs
B **e, Y Liu, X Li, P Yang, W He - Acta Pharmaceutica Sinica B, 2024 - Elsevier
Currently, about 40% of approved drugs and nearly 90% of drug candidates are poorly
water-soluble drugs. Low solubility reduces the likelihood that these drugs can be effectively …
water-soluble drugs. Low solubility reduces the likelihood that these drugs can be effectively …
Berberine-loaded thiolated pluronic F127 polymeric micelles for improving skin permeation and retention
J Niu, M Yuan, C Chen, L Wang, Z Tang… - International Journal …, 2020 - Taylor & Francis
Background Challenges associated with local antibacterial and anti-inflammatory drugs
include low penetration and retention of drugs at the expected action site. Additionally …
include low penetration and retention of drugs at the expected action site. Additionally …
Bile salts: natural surfactants and precursors of a broad family of complex amphiphiles
Bile salts (BSs) are naturally occurring rigid surfactants with a steroidal skeleton and specific
self-assembly and interface behaviors. Using bile salts as precursors, derivatives can be …
self-assembly and interface behaviors. Using bile salts as precursors, derivatives can be …
Mesoporous bioactive glass for synergistic therapy of tumor and regeneration of bone tissue
Y Liu, R Lin, L Ma, H Zhuang, C Feng, J Chang… - Applied Materials …, 2020 - Elsevier
Abstract Treatment of tumorous bone defects needs complete elimination of residual cancer
cells and, at the same time promotion of bone regeneration. Herein, manganese (Mn)-doped …
cells and, at the same time promotion of bone regeneration. Herein, manganese (Mn)-doped …
Brain targeting efficiency of intranasal clozapine-loaded mixed micelles following radio labeling with Technetium-99m
The research objective is to design intranasal (IN) brain targeted CLZ-loaded polymeric
nanomicellar systems (PNMS) aiming to improve central systemic CLZ bioavailability. Direct …
nanomicellar systems (PNMS) aiming to improve central systemic CLZ bioavailability. Direct …
Effect of pharmaceutical excipients on micellization of Pluronic and the application as drug carrier to reverse MDR
Y Li, Y Tian, X Jia, Z Zhang, D Sun, H **e… - Journal of Molecular …, 2023 - Elsevier
Linear amphiphilic triblock copolymers Pluronic, poly (ethylene oxide)-poly (propylene
oxide)-poly (ethylene oxide)(PEO-PPO-PEO) have been widely used in controllable drug …
oxide)-poly (ethylene oxide)(PEO-PPO-PEO) have been widely used in controllable drug …