Psychobiotics and the manipulation of bacteria–gut–brain signals

A Sarkar, SM Lehto, S Harty, TG Dinan, JF Cryan… - Trends in …, 2016 - cell.com
Psychobiotics were previously defined as live bacteria (probiotics) which, when ingested,
confer mental health benefits through interactions with commensal gut bacteria. We expand …

Human secretory IgM: an elusive player in mucosal immunity

E Michaud, C Mastrandrea, N Rochereau, S Paul - Trends in immunology, 2020 - cell.com
Secretory IgMs (SIgMs) were amongst the first identified immunoglobulins. However, their
importance was not fully understood and recent advances have shown they play a key role …

Cannabinoid CB2 receptors in the mouse brain: relevance for Alzheimer's disease

A López, N Aparicio, MR Pazos, MT Grande… - Journal of …, 2018 - Springer
Background Because of their low levels of expression and the inadequacy of current
research tools, CB 2 cannabinoid receptors (CB 2 R) have been difficult to study, particularly …

Bifidobacterium-derived short-chain fatty acids and indole compounds attenuate nonalcoholic fatty liver disease by modulating gut-liver axis

SJ Yoon, JS Yu, BH Min, H Gupta, SM Won… - Frontiers in …, 2023 - frontiersin.org
Emerging evidences about gut-microbial modulation have been accumulated in the
treatment of nonalcoholic fatty liver disease (NAFLD). We evaluated the effect of …

Pathobiont-driven antibody sialylation through IL-10 undermines vaccination

CM Tsai, IA Hajam, JR Caldera, AWT Chiang… - The Journal of Clinical …, 2024 - jci.org
The pathobiont Staphylococcus aureus (Sa) induces nonprotective antibody imprints that
underlie ineffective staphylococcal vaccination. However, the mechanism by which Sa …

Age-related compositional changes and correlations of gut microbiome, serum metabolome, and immune factor in rats

X Zhang, Y Yang, J Su, X Zheng, C Wang, S Chen… - Geroscience, 2021 - Springer
Aging is a complex physiological process associated with degenerative disorder of
metabolism and immune function, which contributes to the occurrence of senile diseases …

Sex differences in pulmonary responses to ozone in mice. Role of the microbiome

Y Cho, G Abu-Ali, H Tashiro, TA Brown… - American journal of …, 2019 - atsjournals.org
We have previously reported that the mouse gut microbiome contributes to pulmonary
responses to ozone, a common asthma trigger, and that short-chain fatty acids, end products …

Benzene exposure induces gut microbiota dysbiosis and metabolic disorder in mice

R Sun, K Xu, S Ji, Y Pu, Z Man, J Ji, M Chen… - Science of The Total …, 2020 - Elsevier
The gut microbiota comprises a multispecies microbial community and is essential for
maintaining health. Benzene is a widespread environmental and occupational pollutant that …

Inhibition of myeloperoxidase at the peak of experimental autoimmune encephalomyelitis restores blood–brain barrier integrity and ameliorates disease severity

H Zhang, A Ray, NM Miller, D Hartwig… - Journal of …, 2016 - Wiley Online Library
Oxidative stress is thought to contribute to disease pathogenesis in the central nervous
system (CNS) disease multiple sclerosis (MS). Myeloperoxidase (MPO), a potent peroxidase …

NAFLD, Helicobacter species and the intestinal microbiome

N Castano-Rodriguez, HM Mitchell… - Best practice & research …, 2017 - Elsevier
Non-alcoholic fatty liver disease (NAFLD) has become the most common chronic liver
disease worldwide. It is well-accepted that gut dysbiosis is associated with NAFLD, however …