Applications of microfluidics and organ-on-a-chip in cancer research

S Regmi, C Poudel, R Adhikari, KQ Luo - Biosensors, 2022 - mdpi.com
Taking the life of nearly 10 million people annually, cancer has become one of the major
causes of mortality worldwide and a hot topic for researchers to find innovative approaches …

Engineered biomimetic membranes for organ-on-a-chip

M Rahimnejad, F Rasouli, S Jahangiri… - ACS Biomaterials …, 2022 - ACS Publications
Organ-on-a-chip (OOC) systems are engineered nanobiosystems to mimic the
physiochemical environment of a specific organ in the body. Among various components of …

Effect of biochemical and biomechanical factors on vascularization of kidney organoid-on-a-chip

HN Lee, YY Choi, JW Kim, YS Lee, JW Choi, T Kang… - Nano …, 2021 - Springer
Kidney organoids derived from the human pluripotent stem cells (hPSCs) recapitulating
human kidney are the attractive tool for kidney regeneration, disease modeling, and drug …

3D bioprinted drug-resistant breast cancer spheroids for quantitative in situ evaluation of drug resistance

S Hong, JM Song - Acta biomaterialia, 2022 - Elsevier
Drug-resistant cancer spheroids were fabricated by three-dimensional (3D) bioprinting for
the quantitative evaluation of drug resistance of cancer cells, which is a very important issue …

Musculoskeletal Organs‐on‐Chips: An Emerging Platform for Studying the Nanotechnology–Biology Interface

Y Wang, P Yung, G Lu, Y Liu, C Ding, C Mao… - Advanced …, 2025 - Wiley Online Library
Nanotechnology‐based approaches are promising for the treatment of musculoskeletal
(MSK) disorders, which present significant clinical burdens and challenges, but their clinical …

From organ-on-a-chip to human-on-a-chip: A review of research progress and latest applications

Y Huang, T Liu, Q Huang, Y Wang - ACS sensors, 2024 - ACS Publications
Organ-on-a-Chip (OOC) technology, which emulates the physiological environment and
functionality of human organs on a microfluidic chip, is undergoing significant technological …

Gastrointestinal organs and organoids-on-a-chip: advances and translation into the clinics

MR Carvalho, LP Yan, B Li, CH Zhang, YL He… - …, 2023 - iopscience.iop.org
Microfluidic organs and organoids-on-a-chip models of human gastrointestinal systems
have been established to recreate adequate microenvironments to study physiology and …

Prevascularized micro-/nano-sized spheroid/bead aggregates for vascular tissue engineering

M Rahimnejad, N Nasrollahi Boroujeni, S Jahangiri… - Nano-Micro Letters, 2021 - Springer
Efficient strategies to promote microvascularization in vascular tissue engineering, a central
priority in regenerative medicine, are still scarce; nano-and micro-sized aggregates and …

Acoustic bioprinting of patient‐derived organoids for predicting cancer therapy responses

H Chen, Z Wu, Z Gong, Y **a, J Li, L Du… - Advanced …, 2022 - Wiley Online Library
Cancer models, which are biologically representative of patient tumors, can predict the
treatment responses and help determine the most appropriate cancer treatment for …

From digital control to digital twins in medicine: A brief review and future perspectives

R Eftimie, A Mavrodin, SPA Bordas - Advances in Applied Mechanics, 2023 - Elsevier
The last few decades have been dominated by the need for digital control of various
processes in biology and medicine. Advances in artificial intelligence (AI) over the last few …