The S100B protein: A multifaceted pathogenic factor more than a biomarker
S100B is a calcium-binding protein mainly concentrated in astrocytes in the nervous system.
Its levels in biological fluids are recognized as a reliable biomarker of active neural distress …
Its levels in biological fluids are recognized as a reliable biomarker of active neural distress …
Blood biomarkers in epilepsy
Robust and accessible biomarkers are greatly needed in epilepsy. Diagnostic and
prognostic precision in the clinic needs to improve, and there is a need for objective …
prognostic precision in the clinic needs to improve, and there is a need for objective …
Fluid biomarkers of neuro-glial injury in human status epilepticus: a systematic review
G Giovannini, S Meletti - International Journal of Molecular Sciences, 2023 - mdpi.com
As per the latest ILAE definition, status epilepticus (SE) may lead to long-term irreversible
consequences, such as neuronal death, neuronal injury, and alterations in neuronal …
consequences, such as neuronal death, neuronal injury, and alterations in neuronal …
Pharmacological modulation of cytokines correlating neuroinflammatory cascades in epileptogenesis
S Vishwakarma, S Singh, TG Singh - Molecular Biology Reports, 2022 - Springer
Epileptic seizure-induced brain injuries include activation of neuroimmune response with
activation of microglia, astrocytes cells releasing neurotoxic inflammatory mediators …
activation of microglia, astrocytes cells releasing neurotoxic inflammatory mediators …
Growing role of S100B protein as a putative therapeutic target for neurological-and nonneurological-disorders
S100B is a calcium-binding protein mainly expressed by astrocytes, but also localized in
other definite neural and extra-neural cell types. While its presence in biological fluids is …
other definite neural and extra-neural cell types. While its presence in biological fluids is …
Cerebral biomarkers and blood-brain barrier integrity in preeclampsia
Cerebral complications in preeclampsia contribute substantially to maternal mortality and
morbidity. There is a lack of reliable and accessible predictors for preeclampsia-related …
morbidity. There is a lack of reliable and accessible predictors for preeclampsia-related …
Mini review: Current status and perspective of S100B protein as a biomarker in daily clinical practice for diagnosis and prognosticating of clinical outcome in patients …
T Abboud, V Rohde, D Mielke - BMC neuroscience, 2023 - Springer
Prognosticating the clinical outcome of neurological diseases is essential to guide treatment
and facilitate decision-making. It usually depends on clinical and radiological findings …
and facilitate decision-making. It usually depends on clinical and radiological findings …
Assessment of prognostic biomarkers in sudden sensorineural hearing loss: a systematic review and meta-analysis
Sudden sensorineural hearing loss (SSNHL) is defined as hearing loss of more than 30 dB
in less than 72 h. SSNHL is a frequent complaint and an emergency in otolaryngology …
in less than 72 h. SSNHL is a frequent complaint and an emergency in otolaryngology …
[HTML][HTML] Neuro-glial degeneration in Status Epilepticus: Exploring the role of serum levels of Neurofilament light chains and S100B as prognostic biomarkers for short …
G Giovannini, R Bedin, N Orlandi, G Turchi… - Epilepsy & Behavior, 2023 - Elsevier
Background The last ILAE definition of Status Epilepticus (SE) highlights that the persistence
of the epileptic activity per se could determine irreversible brain damages that could be …
of the epileptic activity per se could determine irreversible brain damages that could be …
Combined transcriptomics and proteomics forecast analysis for potential biomarker in the acute phase of temporal lobe epilepsy
C Huang, Z You, Y He, J Li, Y Liu, C Peng… - Frontiers in …, 2023 - frontiersin.org
Background Temporal lobe epilepsy (TLE) is a common chronic episodic illness of the
nervous system. However, the precise mechanisms of dysfunction and diagnostic …
nervous system. However, the precise mechanisms of dysfunction and diagnostic …