Neuropathic pain is caused by a lesion or disease of the somatosensory system, including
peripheral fibres (Aβ, Aδ and C fibres) and central neurons, and affects 7–10% of the …

The redefinition of neuropathic pain as “pain arising as a direct consequence of a lesion or
disease affecting the somatosensory system,” which was suggested by the International …

Background New drug treatments, clinical trials, and standards of quality for assessment of
evidence justify an update of evidence-based recommendations for the pharmacological …

Most patients with neuropathic pain symptoms present and are managed in primary care,
with only a minority being referred for specialist clinical assessment and diagnoses …

Different neuroplastic processes can occur along the nociceptive pathways and may be
important in the transition from acute to chronic pain and for diagnosis and development of …

2. Background The history behind this change dates back several years with a long, and at
times, heated debate about the inclusion of the term “dysfunction”[5]. Clinicians with …

Opioids are a mainstay of acute pain management but can have many adverse effects,
contributing to problematic long-term use. Opioid tolerance (increased dose needed for …

Allodynia (pain due to a stimulus that does not usually provoke pain) and hyperalgesia
(increased pain from a stimulus that usually provokes pain) are prominent symptoms in …

Pain medication plays an important role in the treatment of acute and chronic pain
conditions, but some drugs, opioids in particular, have been overprescribed or prescribed …

Importance Chronic pelvic pain (CPP) is a challenging condition that affects an estimated
26% of the world's female population. Chronic pelvic pain accounts for 40% of …