Mitochondrial DNA as a marker of molecular diversity: a reappraisal

N Galtier, B Nabholz, S Glémin, GDD Hurst - Molecular ecology, 2009 - Wiley Online Library
Over the last three decades, mitochondrial DNA has been the most popular marker of
molecular diversity, for a combination of technical ease‐of‐use considerations, and …

The incomplete natural history of mitochondria

JWO Ballard, MC Whitlock - Molecular ecology, 2004 - Wiley Online Library
Mitochondrial DNA (mtDNA) has been used to study molecular ecology and
phylogeography for 25 years. Much important information has been gained in this way, but it …

Mitochondrial DNA mutations in human disease

RW Taylor, DM Turnbull - Nature Reviews Genetics, 2005 - nature.com
The human mitochondrial genome is extremely small compared with the nuclear genome,
and mitochondrial genetics presents unique clinical and experimental challenges. Despite …

Considering evolutionary processes in conservation biology

KA Crandall, ORP Bininda-Emonds, GM Mace… - Trends in ecology & …, 2000 - cell.com
Conservation biologists assign population distinctiveness by classifying populations as
evolutionarily significant units (ESUs). Historically, this classification has included ecological …

A simple and robust statistical test for detecting the presence of recombination

TC Bruen, H Philippe, D Bryant - Genetics, 2006 - academic.oup.com
Recombination is a powerful evolutionary force that merges historically distinct genotypes.
But the extent of recombination within many organisms is unknown, and even determining …

Linkage disequilibrium in humans: models and data

JK Pritchard, M Przeworski - The American Journal of Human Genetics, 2001 - cell.com
In this review, we describe recent empirical and theoretical work on the extent of linkage
disequilibrium (LD) in the human genome, comparing the predictions of simple population …

Mitochondrial genome variation and the origin of modern humans

M Ingman, H Kaessmann, S Pääbo, U Gyllensten - Nature, 2000 - nature.com
The analysis of mitochondrial DNA (mtDNA) has been a potent tool in our understanding of
human evolution, owing to characteristics such as high copy number, apparent lack of …

The inheritance of genes in mitochondria and chloroplasts: laws, mechanisms, and models

CW Birky Jr - Annual review of genetics, 2001 - annualreviews.org
▪ Abstract The inheritance of mitochondrial and chloroplast genes differs from that of nuclear
genes in showing vegetative segregation, uniparental inheritance, intracellular selection …

Coincidence, coevolution, or causation? DNA content, cell size, and the C-value enigma

TR Gregory - Biological reviews, 2001 - cambridge.org
Variation in DNA content has been largely ignored as a factor in evolution, particularly
following the advent of sequence-based approaches to genomic analysis. The significant …

An exact nonparametric method for inferring mosaic structure in sequence triplets

MF Boni, D Posada, MW Feldman - Genetics, 2007 - academic.oup.com
Statistical tests for detecting mosaic structure or recombination among nucleotide
sequences usually rely on identifying a pattern or a signal that would be unlikely to appear …