The schizophrenia syndrome, circa 2024: What we know and how that informs its nature

R Tandon, H Nasrallah, S Akbarian… - Schizophrenia …, 2024 - Elsevier
With new data about different aspects of schizophrenia being continually generated, it
becomes necessary to periodically revisit exactly what we know. Along with a need to review …

Language as a biomarker for psychosis: a natural language processing approach

CM Corcoran, VA Mittal, CE Bearden, RE Gur… - Schizophrenia …, 2020 - Elsevier
Human ratings of conceptual disorganization, poverty of content, referential cohesion and
illogical thinking have been shown to predict psychosis onset in prospective clinical high risk …

Integrative omics of schizophrenia: from genetic determinants to clinical classification and risk prediction

F Guan, T Ni, W Zhu, LK Williams, LB Cui, M Li… - Molecular …, 2022 - nature.com
Schizophrenia (SCZ) is a debilitating neuropsychiatric disorder with high heritability and
complex inheritance. In the past decade, successful identification of numerous susceptibility …

Neuroimaging in schizophrenia

MS Keshavan, G Collin, S Guimond… - … Clinics of North …, 2019 - pmc.ncbi.nlm.nih.gov
Psychotic disorders are mental illnesses characterized by difficulties in reality testing1.
Schizophrenia is a severe and chronic psychotic disorder with a life time prevalence of …

Neurodegenerative model of schizophrenia: Growing evidence to support a revisit

WS Stone, MR Phillips, LH Yang, LS Kegeles… - Schizophrenia …, 2022 - Elsevier
Multidimensional progressive declines in the absence of standard biomarkers for
neurodegeneration are observed commonly in the development of schizophrenia, and are …

[HTML][HTML] Updating and characterizing neuroanatomical markers in high-risk subjects, recently diagnosed and chronic patients with schizophrenia: A revised coordinate …

D Liloia, C Brasso, F Cauda, L Mancuso, A Nani… - Neuroscience & …, 2021 - Elsevier
Characterizing neuroanatomical markers of different stages of schizophrenia (SZ) to assess
pathophysiological models of how the disorder develops is an important target for the …

Subty** schizophrenia patients based on patterns of structural brain alterations

Y **ao, W Liao, Z Long, B Tao, Q Zhao… - Schizophrenia …, 2022 - academic.oup.com
Schizophrenia is a complex and heterogeneous syndrome. Whether quantitative imaging
biomarkers can identify discrete subgroups of patients as might be used to foster …

The temporal dynamics of transition to psychosis in individuals at clinical high-risk (CHR-P) shows negative prognostic effects of baseline antipsychotic exposure: a …

A Raballo, M Poletti, A Preti - Translational Psychiatry, 2023 - nature.com
Meta-analytic evidence indicates that baseline exposure to antipsychotics (AP) in individuals
at clinical high-risk for psychosis (CHR-P) is associated with an even higher risk of transition …

How machine learning is powering neuroimaging to improve brain health

NM Singh, JB Harrod, S Subramanian, M Robinson… - Neuroinformatics, 2022 - Springer
This report presents an overview of how machine learning is rapidly advancing clinical
translational imaging in ways that will aid in the early detection, prediction, and treatment of …

Schizophrenia: a narrative review of etiopathogenetic, diagnostic and treatment aspects

L Orsolini, S Pompili, U Volpe - Journal of Clinical Medicine, 2022 - mdpi.com
Although schizophrenia is currently conceptualized as being characterized as a syndrome
that includes a collection of signs and symptoms, there is strong evidence of heterogeneous …