Iron Oxide Nanoparticles as T1 Contrast Agents for Magnetic Resonance Imaging: Fundamentals, Challenges, Applications, and Prospectives

M Jeon, MV Halbert, ZR Stephen… - Advanced Materials, 2021 - Wiley Online Library
Gadolinium‐based chelates are a mainstay of contrast agents for magnetic resonance
imaging (MRI) in the clinic. However, their toxicity elicits severe side effects and the Food …

[HTML][HTML] Multifunctional magnetic iron oxide nanoparticles: an advanced platform for cancer theranostics

S Zhao, X Yu, Y Qian, W Chen, J Shen - Theranostics, 2020 - ncbi.nlm.nih.gov
Multifunctional magnetic nanoparticles and derivative nanocomposites have aroused great
concern for multimode imaging and cancer synergistic therapies in recent years. Among the …

Structure–relaxivity relationships of magnetic nanoparticles for magnetic resonance imaging

Z Zhou, L Yang, J Gao, X Chen - Advanced Materials, 2019 - Wiley Online Library
Magnetic nanoparticles (MNPs) have been extensively explored as magnetic resonance
imaging (MRI) contrast agents. With the increasing complexity in the structure of modern …

Mesoporous silica and organosilica nanoparticles: physical chemistry, biosafety, delivery strategies, and biomedical applications

JG Croissant, Y Fatieiev, A Almalik… - Advanced healthcare …, 2018 - Wiley Online Library
Predetermining the physico‐chemical properties, biosafety, and stimuli‐responsiveness of
nanomaterials in biological environments is essential for safe and effective biomedical …

Degradability and clearance of inorganic nanoparticles for biomedical applications

G Yang, SZF Phua, AK Bindra, Y Zhao - Advanced Materials, 2019 - Wiley Online Library
Inorganic nanoparticles with tunable and diverse properties hold tremendous potential in the
field of nanomedicine, while having non‐negligible toxicity concerns in healthy …

Degradability and clearance of silicon, organosilica, silsesquioxane, silica mixed oxide, and mesoporous silica nanoparticles

JG Croissant, Y Fatieiev, NM Khashab - Advanced materials, 2017 - Wiley Online Library
The biorelated degradability and clearance of siliceous nanomaterials have been
questioned worldwide, since they are crucial prerequisites for the successful translation in …

Iron oxide nanoparticle based contrast agents for magnetic resonance imaging

Z Shen, A Wu, X Chen - Molecular pharmaceutics, 2017 - ACS Publications
Magnetic iron oxide nanoparticles (MIONs) have attracted enormous attention due to their
wide applications, including for magnetic separation, for magnetic hyperthermia, and as …

Multifunctional Theranostic Nanoparticles Based on Exceedingly Small Magnetic Iron Oxide Nanoparticles for T1-Weighted Magnetic Resonance Imaging and …

Z Shen, T Chen, X Ma, W Ren, Z Zhou, G Zhu… - ACS …, 2017 - ACS Publications
The recently emerged exceedingly small magnetic iron oxide nanoparticles (ES-MIONs)(< 5
nm) are promising T 1-weighted contrast agents for magnetic resonance imaging (MRI) due …

Magnetic nanomaterials as contrast agents for MRI

S Caspani, R Magalhães, JP Araújo, CT Sousa - Materials, 2020 - mdpi.com
Magnetic Resonance Imaging (MRI) is a powerful, noninvasive and nondestructive
technique, capable of providing three-dimensional (3D) images of living organisms. The use …

Magnetic iron oxide nanoparticles as T 1 contrast agents for magnetic resonance imaging

Y Bao, JA Sherwood, Z Sun - Journal of Materials Chemistry C, 2018 - pubs.rsc.org
Ultrasmall iron oxide nanoparticles have recently attracted much attention as T1 (positive)
contrast agents for magnetic resonance imaging to serve as safer alternatives to gadolinium …