'Home inspections' for life sciences companies going public before clinical proof-of-concept

A Bespalov, R Miller, CH Emmerich - Drug Discovery Today, 2024 - Elsevier
For the period from 2010 to 2021, we have observed a phenomenon of life sciences
companies conducting Initial Public Offerings (IPOs) without any assets that have …

New drugs and stock market: a machine learning framework for predicting pharma market reaction to clinical trial announcements

S Budennyy, A Kazakov, E Kovtun, L Zhukov - Scientific Reports, 2023 - nature.com
Pharmaceutical companies operate in a strictly regulated and highly risky environment in
which a single slip can lead to serious financial implications. Accordingly, the …

UK paediatric clinical trial protocols: A review of guidance for participant management and care in the event of premature termination

H Pluess-Hall, P Smith, J Menzies - Clinical Trials, 2024 - journals.sagepub.com
Background/Aims: Clinical trials provide an opportunity to identify new treatments and can
offer patients access to treatments otherwise unavailable. However, approximately 10% of …

Valuing pharmaceutical drug innovations

G Aryal, F Ciliberto, LE Farmer… - arxiv preprint arxiv …, 2022 - arxiv.org
We propose a methodology to estimate the market value of pharmaceutical drugs. Our
approach combines an event study with a model of discounted cash flows and uses stock …

How does news affect biopharma stock prices?: An event study

J Cho, M Singh, AW Lo - Plos one, 2024 - journals.plos.org
We investigate the impact of information on biopharmaceutical stock prices via an event
study encompassing 503,107 news releases from 1,012 companies. We distinguish …

Risk and return in the biotech industry

H Bruneo, E Giacomini, G Iannotta, A Murthy… - International Journal of …, 2024 - emerald.com
Purpose Biotech companies stand as key actors in pharmaceutical innovation. The high risk
and long timelines inherent with their R&D investments might hinder their access to funding …

[HTML][HTML] A Double-Blind Trial Platform Based on Distributed Ledger Technology

YH Yeh, SC Hsueh, TY Liang - Electronics, 2023 - mdpi.com
In the pharmaceutical research and development process, the third phase of clinical trials
involves double-blind trials to mitigate the influence of human subjective awareness on the …

[PDF][PDF] Inflection Point: How Clinical Trial Results Impact Biopharma Valuations

M GORES, C FRANCESCO - iqvia.com
Furthermore, we will elaborate on the practical implications of understanding those drivers of
value inflection. For example, how such insight may inform strategic decisions and help …