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[HTML][HTML] Cell fate decisions, transcription factors and signaling during early retinal development
R Diacou, P Nandigrami, A Fiser, W Liu… - Progress in retinal and …, 2022 - Elsevier
The development of the vertebrate eyes is a complex process starting from anterior-posterior
and dorso-ventral patterning of the anterior neural tube, resulting in the formation of the eye …
and dorso-ventral patterning of the anterior neural tube, resulting in the formation of the eye …
Patterning and development of photoreceptors in the human retina
KA Hussey, SE Hadyniak… - Frontiers in cell and …, 2022 - frontiersin.org
Humans rely on visual cues to navigate the world around them. Vision begins with the
detection of light by photoreceptor cells in the retina, a light-sensitive tissue located at the …
detection of light by photoreceptor cells in the retina, a light-sensitive tissue located at the …
[HTML][HTML] Dynamic axonal translation in develo** and mature visual circuits
T Shigeoka, H Jung, J Jung, B Turner-Bridger, J Ohk… - Cell, 2016 - cell.com
Local mRNA translation mediates the adaptive responses of axons to extrinsic signals, but
direct evidence that it occurs in mammalian CNS axons in vivo is scant. We developed an …
direct evidence that it occurs in mammalian CNS axons in vivo is scant. We developed an …
[HTML][HTML] Overlap** transcriptional programs promote survival and axonal regeneration of injured retinal ganglion cells
Injured neurons in the adult mammalian central nervous system often die and seldom
regenerate axons. To uncover transcriptional pathways that could ameliorate these …
regenerate axons. To uncover transcriptional pathways that could ameliorate these …
Congenital aniridia beyond black eyes: from phenotype and novel genetic mechanisms to innovative therapeutic approaches
Congenital PAX6-aniridia, initially characterized by the absence of the iris, has progressively
been shown to be associated with other developmental ocular abnormalities and systemic …
been shown to be associated with other developmental ocular abnormalities and systemic …
Roles of HIFs and VEGF in angiogenesis in the retina and brain
Vascular development in the mammalian retina is a paradigm for CNS vascular
development in general, and its study is revealing fundamental mechanisms that explain the …
development in general, and its study is revealing fundamental mechanisms that explain the …
Transgenic strategies for combinatorial expression of fluorescent proteins in the nervous system
Detailed analysis of neuronal network architecture requires the development of new
methods. Here we present strategies to visualize synaptic circuits by genetically labelling …
methods. Here we present strategies to visualize synaptic circuits by genetically labelling …
Intrinsically different retinal progenitor cells produce specific types of progeny
C Cepko - Nature Reviews Neuroscience, 2014 - nature.com
Lineage studies conducted in the retina more than 25 years ago demonstrated the
multipotency of retinal progenitor cells (RPCs). The number and types of cells produced by …
multipotency of retinal progenitor cells (RPCs). The number and types of cells produced by …
Gene regulatory networks controlling temporal patterning, neurogenesis, and cell-fate specification in mammalian retina
P Lyu, T Hoang, CP Santiago, ED Thomas, AE Timms… - Cell Reports, 2021 - cell.com
Gene regulatory networks (GRNs), consisting of transcription factors and their target sites,
control neurogenesis and cell-fate specification in the develo** central nervous system. In …
control neurogenesis and cell-fate specification in the develo** central nervous system. In …
Electroporation and RNA interference in the rodent retina in vivo and in vitro
T Matsuda, CL Cepko - Proceedings of the National Academy of Sciences, 2004 - pnas.org
The large number of candidate genes made available by comprehensive genome analysis
requires that relatively rapid techniques for the study of function be developed. Here, we …
requires that relatively rapid techniques for the study of function be developed. Here, we …