Brain-derived neurotrophic factor (BDNF) is widely accepted for its involvement in resilience
and antidepressant drug action, is a common genetic locus of risk for mental illnesses, and …

Neurobiological systems may be particularly susceptible to the deleterious impact of
childhood trauma, and the impact of childhood trauma on development and subsequent …

Through incorporating both physical and psychological forms of stressors, a variety of rodent
models have provided important insights into the understanding of stress physiology …

Irritable bowel syndrome (IBS) is a complex multifactorial condition including alterations of
the gut–brain axis, intestinal permeability, mucosal neuro-immune interactions, and …

Currently, the diagnosis of major depressive disorder (MDD) mainly relies on clinical
examination and subjective evaluation of depressive symptoms. There is no non-invasive …

Depression is a devastating psychiatric disorder caused by a combination of genetic
predisposition and life events, mainly exposure to stress. Early life stress (ELS) in particular …

Much has been documented on the association between stress and health. Both direct and
indirect pathways have been identified and explored extensively, hel** us understand …

Major depression is a common long-lasting or recurrent psychiatric disease with high
lifetime prevalence and high incidence of suicide. The main purpose of the current study …

Background Social determinants of health (SDoHs) are nonmedical factors that significantly
impact health and longevity. We found no published reviews on the biology of SDoHs in …

Brain-derived neurotrophic factor (BDNF) is involved in many functions such as neuronal
growth, survival, synaptic plasticity and memorization. Altered expression levels are …