Summary Coronavirus disease 2019 (COVID-19) currently has few effective treatments.
Given the uncertainty surrounding the effectiveness and uptake of a vaccine, it is important …

Rheumatoid arthritis (RA) is a chronic, persistent autoimmune disease that causes severe
joint tissue damage and irreversible disability. Cumulative evidence suggests that patients …

Progressive fibrosis is a feature of aging and chronic tissue injury in multiple organs,
including the kidney and heart. Glioma-associated oncogene 1 expressing (Gli1+) cells are …

Background Proteomic profiling may allow identification of plasma proteins that associate
with subsequent changesin kidney function, elucidating biologic processes underlying the …

Inflammation in chronic kidney disease (CKD) is mostly due to activation of the innate
immune system, in which Interleukin-1 (IL-1) is a key player. Anemia of CKD may also be …

Bilirubin is a well-known neurotoxin in newborn infants; however, current evidence has
shown that a higher serum bilirubin concentration in physiological ranges is associated with …

Introduction Chronic kidney disease (CKD) is a common comorbidity of rheumatoid arthritis
(RA). The association of longitudinal RA disease activity with long-term kidney function has …

The current standard of care measures for kidney function, proteinuria, and serum creatinine
(SCr) are poor predictors of early-stage kidney disease. Measures that can detect chronic …

Introduction Despite the risk of incident chronic kidney disease among the patients with
rheumatoid arthritis (RA), the association of RA and the risk of end-stage renal disease …

Objectives The impact of individual biological/targeted synthetic DMARD (b/tsDMARD) on
kidney function in patients with RA remains unclear. This study aimed to determine the …