Cadherin signaling in cancer: its functions and role as a therapeutic target
W Yu, L Yang, T Li, Y Zhang - Frontiers in oncology, 2019 - frontiersin.org
Cadherin family includes lists of transmembrane glycoproteins which mediate calcium-
dependent cell-cell adhesion. Cadherin-mediated adhesion regulates cell growth and …
dependent cell-cell adhesion. Cadherin-mediated adhesion regulates cell growth and …
Familial gastric cancer: genetic susceptibility, pathology, and implications for management
Familial gastric cancer comprises at least three major syndromes: hereditary diffuse gastric
cancer, gastric adenocarcinoma and proximal polyposis of the stomach, and familial …
cancer, gastric adenocarcinoma and proximal polyposis of the stomach, and familial …
A central role for cadherin signaling in cancer
Cadherins are homophilic adhesion molecules with important functions in cell-cell adhesion,
tissue morphogenesis, and cancer. In epithelial cells, E-cadherin accumulates at areas of …
tissue morphogenesis, and cancer. In epithelial cells, E-cadherin accumulates at areas of …
Decreased expression of long noncoding RNA GAS5 indicates a poor prognosis and promotes cell proliferation in gastric cancer
Background Gastric cancer is the second leading cause of cancer death and remains a
major clinical challenge due to poor prognosis and limited treatment options. Long …
major clinical challenge due to poor prognosis and limited treatment options. Long …
Downregulated long noncoding RNA MEG3 is associated with poor prognosis and promotes cell proliferation in gastric cancer
Long noncoding RNAs (lncRNAs) have emerged recently as major players in governing
fundamental biological processes, and many of which are altered in expression and likely to …
fundamental biological processes, and many of which are altered in expression and likely to …
Epithelial E-and P-cadherins: role and clinical significance in cancer
E-cadherin and P-cadherin are major contributors to cell–cell adhesion in epithelial tissues,
playing pivotal roles in important morphogenetic and differentiation processes during …
playing pivotal roles in important morphogenetic and differentiation processes during …
E-cadherin's dark side: possible role in tumor progression
In the context of cancer, E-cadherin has traditionally been categorized as a tumor
suppressor, given its essential role in the formation of proper intercellular junctions, and its …
suppressor, given its essential role in the formation of proper intercellular junctions, and its …
Somatic mutations and deletions of the E-cadherin gene predict poor survival of patients with gastric cancer
Purpose The prognosis of gastric cancer (GC) is poor, and the molecular pathogenesis
players are vastly unknown. Surgery remains the primary option in GC treatment. The aim of …
players are vastly unknown. Surgery remains the primary option in GC treatment. The aim of …
[HTML][HTML] Cadherin expression and EMT: a focus on gliomas
Cadherins are calcium-binding proteins with a pivotal role in cell adhesion and tissue
homeostasis. The cadherin-dependent mechanisms of cell adhesion and migration are …
homeostasis. The cadherin-dependent mechanisms of cell adhesion and migration are …
Diffuse gastric cancer: a summary of analogous contributing factors for its molecular pathogenicity
Gastric cancer is the third leading cause of cancer-related deaths and ranks as the fifth most
common cancer worldwide. Incidence and mortality differ depending on the geographical …
common cancer worldwide. Incidence and mortality differ depending on the geographical …